Introducing Genes into Mammalian Cells: Viral Vectors.
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Summary
Over the years, many different viral vector systems have been developed to take advantage of the specific biological properties and tropisms of a large number of mammalian viruses to introduce and express genes in mammalian cells.
- Type
- review
- Published
- 2020-05-26
- Cited by
- 77
- References
- 133
- Access
- Open access
- OpenAlex
- https://openalex.org/W3030473135
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:218908033
Keywords
Gene, Computational biology, Biology, Viral vector, Vector (molecular biology)
References
- Optimization of adenoviral vector-mediated transgene expression in the canine brain in vivo, and in canine glioma cells in vitro.
- Strategies for targeting lentiviral vectors.
- Methods for the production of first generation adenoviral vectors.
- Adenovirus vectors for human gene therapy.
- The human immunodeficiency virus type-1 central DNA flap is a crucial determinant for lentiviral vector nuclear import and gene transduction of human hematopoietic stem cells.
- Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences
- Efficient lentiviral transduction of liver requires cell cycling in vivo
- An infectious transfer and expression system for genomic DNA loci in human and mouse cells
- Production and Characterization of Improved Adenovirus Vectors with the E1, E2b, and E3 Genes Deleted
- Nucleotide sequence and organization of the adeno-associated virus 2 genome
- Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element Enhances Expression of Transgenes Delivered by Retroviral Vectors
- Production of soluble mammalian proteins in Escherichia coli: identification of protein features that correlate with successful expression
- Woodchuck Hepatitis Virus Contains a Tripartite Posttranscriptional Regulatory Element
- Characterization of 911: A New Helper Cell Line for the Titration and Propagation of Early Region 1-Deleted Adenoviral Vectors
- Systemic delivery of genes to striated muscles using adeno-associated viral vectors
- Regulated delivery of therapeutic proteins after in vivo somatic cell gene transfer.
- New Helper Cells and Matched Early Region 1-Deleted Adenovirus Vectors Prevent Generation of Replication-Competent Adenoviruses
- Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector.
- A secreted luciferase for ex vivo monitoring of in vivo processes
- Lentiviral vectors encoding tetracycline-dependent repressors and transactivators for reversible knockdown of gene expression: a comparative study
Cited by
- Gene Therapy Using a miniCEP290 Fragment Delays Photoreceptor Degeneration in a Mouse Model of Leber Congenital Amaurosis
- Dorsal raphé nucleus glucocorticoid receptors inhibit tph2 gene expression in male C57BL/6J mice
- Transcriptome Profiling of Neovascularized Corneas Reveals miR-204 as a Multi-target Biotherapy Deliverable by rAAVs
- Down-regulation of microRNA-203-3p initiates type 2 pathology during schistosome infection via elevation of interleukin-33
- Adeno-associated Virus Genome Population Sequencing Achieves Full Vector Genome Resolution and Reveals Human-Vector Chimeras
- Low Seroprevalence of Neutralizing Antibodies Targeting Two Clade F AAV in Humans
- A Rationally Engineered Capsid Variant of AAV9 for Systemic CNS-Directed and Peripheral Tissue-Detargeted Gene Delivery in Neonates
- Intravenous Infusion of AAV for Widespread Gene Delivery to the Nervous System
- High-Throughput Quantification of In Vivo Adeno-Associated Virus Transduction with Barcoded Non-Coding RNAs
- Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis
- Effective and Accurate Gene Silencing by a Recombinant AAV-Compatible MicroRNA Scaffold.
- Selective effects of dorsal raphé nucleus glucocorticoid receptor deletion on depression-like behavior in female C57BL/6J mice.
- Bone-Targeting AAV-Mediated Gene Silencing in Osteoclasts for Osteoporosis Therapy
- Structural characterization of a novel human adeno-associated virus capsid with neurotropic properties
- AAV-Genome Population Sequencing of Vectors Packaging CRISPR Components Reveals Design-Influenced Heterogeneity
- Precision Cas9 Genome Editing in vivo with All-in-one, Self-targeting AAV Vectors
- Two-Plasmid Packaging System for Recombinant Adeno-Associated Virus
- Viral vector platforms within the gene therapy landscape
- The skeletal muscle circadian clock regulates sarcomere length homeostasis through titin splicing
- Low-Dose Recombinant Adeno-Associated Virus-Mediated Inhibition of Vascular Endothelial Growth Factor Can Treat Neovascular Pathologies Without Inducing Retinal Vasculitis
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