Medial temporal lobe connectivity and its associations with cognition in early Alzheimer’s disease
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Summary
Functional connectivity between the medial temporal lobe and the anterior-temporal system is reduced in the earliest stages of Alzheimer’s disease, before connectivity with the posterior-medial system is affected.
- Type
- article
- Published
- 2020-04-01
- Cited by
- 259
- References
- 83
- Access
- Open access
- OpenAlex
- https://openalex.org/W3014686944
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:215409167
Keywords
Perirhinal cortex, Temporal lobe, Cingulum (brain), Neuroscience, Entorhinal cortex
References
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- Brain Amyloid-β Burden Is Associated with Disruption of Intrinsic Functional Connectivity within the Medial Temporal Lobe in Cognitively Normal Elderly
- Elevated hippocampal resting-state connectivity underlies deficient neurocognitive function in aging
- Anterior and Posterior MTL Networks in Aging and MCI
- The Insight ToolKit image registration framework
- Functional organization of the hippocampal longitudinal axis
- Mild cognitive impairment as a diagnostic entity
- Quantitative Investigation of Connections of the Prefrontal Cortex in the Human and Macaque using Probabilistic Diffusion Tractography
- Two cortical systems for memory-guided behaviour
- IC‐P‐161: Semantic memory impairment in Alzheimer's disease and frontotemporal dementia is associated with semantic network degradation
Cited by
- Organization of cortico-hippocampal networks in the human brain
- Rodent mnemonic similarity task performance requires the prefrontal cortex
- Bundle-specific associations between white matter microstructure and Aβ and tau pathology at their connecting cortical endpoints in older adults at risk of Alzheimer’s disease
- Alzheimer’s pathology is associated with dedifferentiation of functional memory networks in aging
- Impaired Expression of GABA Signaling Components in the Alzheimer’s Disease Middle Temporal Gyrus
- Early Dendritic Dystrophy in Human Brains With Primary Age-Related Tauopathy
- Longitudinal stability of medial temporal lobe connectivity is associated with tau-related memory decline
- Association of CSF Biomarkers With Hippocampal-Dependent Memory in Preclinical Alzheimer Disease
- Impairment of Spike-Timing-Dependent Plasticity at Schaffer Collateral-CA1 Synapses in Adult APP/PS1 Mice Depends on Proximity of Aβ Plaques
- Stereoscopic Depth Perception and Visuospatial Dysfunction in Alzheimer’s Disease
- Advances in neuroimaging to support translational medicine in dementia
- Methylene blue and photobiomodulation recover cognitive impairment in hepatic encephalopathy through different effects on cytochrome c-oxidase.
- Reduced Repetition Suppression in Aging is Driven by Tau–Related Hyperactivity in Medial Temporal Lobe
- Early stages of tau pathology and its associations with functional connectivity, atrophy and memory
- Structural and Functional Disruption of Salience Network in Distinguishing Subjective Cognitive Decline and Amnestic Mild Cognitive Impairment.
- Default mode network connectivity and cognition in the aging brain: The effect of age, sex, and APOE genotype
- Mapping of impaired functional connectivity during memory phases in Alzheimer's disease and its association with cortical β-amyloid
- Update on neuroimaging in Alzheimer’s disease
- Memory precision of object-location binding is unimpaired in APOE ε4-carriers with spatial navigation deficits
- Bundle-specific associations between white matter microstructure and Aβ and tau pathology in preclinical Alzheimer’s disease
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