Emerging strategies for enhancing the homing of hematopoietic stem cells to the bone marrow after transplantation.
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Summary
The current clinical methods used to overcome graft failures and their flaws are discussed and what are the new approaches developed in the past 10-12 years to selectively deliver the hematopoietic stem cells in the bone marrow by adopting proper targeting strategies that can help revolutionize the field of regenerative and translational medicine.
- Type
- review
- Published
- 2020-03-07
- Cited by
- 13
- References
- 137
- OpenAlex
- https://openalex.org/W3009820174
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:212666994
Keywords
Homing (biology), Biology, Stem cell, Haematopoiesis, Bone marrow
References
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- Effects of Gamma Radiation on Bone-Marrow Stromal Cells
- Higher doses of CD34+ progenitors are associated with improved overall survival without increasing GVHD in reduced intensity conditioning allogeneic transplant recipients with clinically advanced disease
- Graft failure after allogeneic hematopoietic stem cell transplantation.
- Peritransplantation Ruxolitinib Prevents Acute Graft-versus-Host Disease in Patients with Myelofibrosis Undergoing Allogenic Stem Cell Transplantation.
- Parvovirus B19 infection in adult patients after allogeneic stem cell transplantation: our experience of five cases and literature review
- High CD34(+) cell counts decrease hematologic toxicity of autologous peripheral blood progenitor cell transplantation.
- Graft rejection by cytolytic T cells. Specificity of the effector mechanism in the rejection of allogeneic marrow.
- Pathways implicated in stem cell migration: the SDF-1/CXCR4 axis.
- Hematopoietic stem cells.
- Predominant or complete recipient T‐cell chimerism following alemtuzumab‐based allogeneic transplantation is reversed by donor lymphocytes and not associated with graft failure
- Mild heat treatment primes human CD34+ cord blood cells for migration towards SDF-1α and enhances engraftment in an NSG mouse model
- Pulse exposure of haematopoietic grafts to prostaglandin E2 in vitro facilitates engraftment and recovery
- Morphology of irradiated microvasculature: a combined in vivo and electron-microscopic study.
- Clinical Role of Human Leukocyte Antigen in Health and Disease
- Clinical evidence for an engraftment syndrome associated with early and steep neutrophil recovery after autologous blood stem cell transplantation.
- Enhancing hematopoietic stem cell transplantation efficacy by mitigating oxygen shock
- Early and late graft-failure after transplants
- Irradiation induces bone injury by damaging bone marrow microenvironment for stem cells
Cited by
- Tonsil-derived mesenchymal stem cells enhance allogeneic bone marrow engraftment via collagen IV degradation
- Haptoglobin is an early indicator of survival after radiation-induced severe injury and bone marrow transplantation in mice
- Injectable bone marrow microniches by co-culture of HSPCs with MSCs in 3D microscaffolds promote hematopoietic reconstitution from acute lethal radiation
- Nanoparticles targeting hematopoietic stem and progenitor cells: Multimodal carriers for the treatment of hematological diseases
- The quest for the holy grail: overcoming challenges in expanding human hematopoietic stem cells for clinical use
- Decoding bone-inspired and cell-instructive cues of scaffolds for bone tissue engineering
- Serum sSelectin-L is an early specific indicator of radiation injury
- Phenolic Composition of Crataegus monogyna Jacq. Extract and Its Anti-Inflammatory, Hepatoprotective, and Antileukemia Effects
- FoxO1 regulates human haematopoietic stem cells self-renewal and engraftment
- Successful of autologous hematopoietic stem cell mobilization with plerixafor combined with G-CSF in pediatric neuroblastoma patients, a single center experience.
- Exploring the Potential of Medicinal Plants in Bone Marrow Regeneration and Hematopoietic Stem Cell Therapy
- Cell-Based Therapeutic Strategies for Autoimmune Diseases
- Additional file 1 of Haptoglobin is an early indicator of survival after radiation-induced severe injury and bone marrow transplantation in mice
- Additional file 1 of Haptoglobin is an early indicator of survival after radiation-induced severe injury and bone marrow transplantation in mice
- Role of Stem Cells in Cancer Therapeutics
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