Modulation of NMDA receptor by miR-219 in the amygdala and hippocampus of patients with mesial temporal lobe epilepsy.
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Summary
It is indicated that miR-219 has a possible regulatory role in excitatory neurotransmission in patients with epilepsy, contributing to the new avenue of miRNA biology in drug-resistant epilepsy, reserving huge potential for future applications and clinical interventions in conjunction with existing therapies.
- Type
- article
- Published
- 2020-02-25
- Cited by
- 16
- References
- 44
- OpenAlex
- https://openalex.org/W3008406345
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:211267178
Keywords
Epilepsy, Hippocampal sclerosis, Temporal lobe, Neuroscience, Hippocampus
References
- The neuronal microRNA system
- Identification of altered microRNAs in serum of a mouse model of Parkinson's disease.
- Inhibitory RNA in epilepsy: Research tool and therapeutic perspectives
- miRNAs in Neurodegeneration
- Small RNAs have a large impact
- Molecular determinants of dysregulated GABAergic gene expression in the prefrontal cortex of subjects with schizophrenia.
- The intra-molecular activation mechanisms of the dimeric metabotropic glutamate receptor 1 differ depending on the type of G proteins.
- Amygdala gene expression of NMDA and GABAA receptors in patients with mesial temporal lobe epilepsy
- GABA actions and ionic plasticity in epilepsy.
- GABAA receptor trafficking and its role in the dynamic modulation of neuronal inhibition
- The descriptive epidemiology of epilepsy-a review
- MiR-219 Protects Against Seizure in the Kainic Acid Model of Epilepsy
- Excitatory Amino Acid Transmitters in Epilepsy
- Alterations in miRNA Levels in the Dentate Gyrus in Epileptic Rats
- Glutamate receptor RNA editing in health and disease
- Antagomirs targeting microRNA-134 increase hippocampal pyramidal neuron spine volume in vivo and protect against pilocarpine-induced status epilepticus
- Expression profile of microRNAs in rat hippocampus following lithium-pilocarpine-induced status epilepticus.
- MicroRNAs in Neuronal Communication
- Altered microRNA Expression in Peripheral Blood Mononuclear Cells from Young Patients with Schizophrenia
- Brain and Blood microRNA Expression Profiling of Ischemic Stroke, Intracerebral Hemorrhage, and Kainate Seizures
Cited by
- Revisiting the role of neurotransmitters in epilepsy: An updated review.
- Synaptic Reshaping and Neuronal Outcomes in the Temporal Lobe Epilepsy
- Multi‐omic strategies applied to the study of pharmacoresistance in mesial temporal lobe epilepsy
- Roles of N-Methyl-D-Aspartate Receptors (NMDARs) in Epilepsy
- Targeting NMDA Receptor Complex in Management of Epilepsy
- Role of miR-219a-5p in regulating NMDAR in nonylphenol-induced synaptic plasticity damage.
- Clinical Correlation of Altered Molecular Signatures in Epileptic Human Hippocampus and Amygdala
- The role of microRNAs in neurobiology and pathophysiology of the hippocampus
- Epigenetic regulation in epilepsy: A novel mechanism and therapeutic strategy for epilepsy.
- Impaired Response to Mismatch Novelty in the Li2+-Pilocarpine Rat Model of TLE: Correlation with Hippocampal Monoaminergic Inputs
- MicroRNA-mediated regulation of neurotransmitter receptors in epilepsy: A systematic review.
- The potential therapeutic role of berberine in treating epilepsy focusing on temporal lobe epilepsy: State of art and ongoing perspective.
- Alteration of microRNA expression in lymphocytes in patients with first-episode schizophrenia
- The Protective Role of Aquaporin 4 (AQP4) in Temporal Lobe Epilepsy: Yes or No?
- Elav-Gal4> Mir-219 Induces Changes in Developmental Survival and Behavior in Drosophila Growth
- Alteration of microRNA expression in lymphocytes in patients with first-episode schizophrenia
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