Re-epithelialization and immune cell behaviour in an ex vivo human skin model
Explore this paper's citation graph
Summary
A novel wound model based on application of negative pressure and its effects for epidermal regeneration and immune cell behaviour is presented, which recapitulates the main features of epithelial wound regeneration, and can be applied for testing wound healing therapies and investigating underlying mechanisms.
- Type
- article
- Published
- 2020-01-08
- Cited by
- 6,596
- References
- 57
- Access
- Open access
- OpenAlex
- https://openalex.org/W3004227146
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:210044839
Keywords
Epidermis (zoology), Suction blister, Wound healing, Ex vivo, Keratinocyte
References
- Pimecrolimus leads to an apoptosis-induced depletion of T cells but not Langerhans cells in patients with atopic dermatitis.
- Biological role of matrix metalloproteinases: a critical balance
- Fate of human keratinocytes during reepithelialization in an organotypic culture model.
- Suction blister device for separation of viable epidermis from dermis.
- Investigation of the cutaneous response to recall antigen in humans in vivo
- Dermo-epidermal separation with suction. Electron microscopic and histochemical study of initial events of blistering on human skin.
- Response to Comment on “The Vast Majority of CLA+ T Cells Are Resident in Normal Skin”
- Matrix Metalloproteinases (MMP-2 and MMP-9) of the Oral Cavity: Cellular Origin and Relationship to Periodontal Status
- Interstitial collagenase is required for angiogenesis in vitro.
- MMP-13 plays a role in keratinocyte migration, angiogenesis, and contraction in mouse skin wound healing.
- Advances in wound healing: topical negative pressure therapy
- Human mast cells produce matrix metalloproteinase 9
- Mechanisms of wound reepithelialization: hints from a tissue‐engineered reconstructed skin to long‐standing questions
- A structural scaffolding of intermediate filaments in health and disease.
- Basal lamina components in experimentally induced skin blisters.
- Changes in keratinocyte maturation during wound healing.
- Localization of basement membrane components after dermal-epidermal junction separation.
- Sheet preparations expose the dermal nerve plexus of human skin and render the dermal nerve end organ accessible to extensive analysis.
- Metalloproteinases and Wound Healing
- Blister fluid T lymphocytes during toxic epidermal necrolysis are functional cytotoxic cells which express human natural killer (NK) inhibitory receptors
Cited by
- Cross-dimensional magnitude interaction is modulated by representational noise: evidence from space–time interaction
- Many-body Green's function theory of electrons and nuclei beyond the Born-Oppenheimer approximation
- Analytical Criteria for Magnetization Reversal in a φ0 Josephson Junction
- The psychological correlates of distinct neural states occurring during wakeful rest
- In silico investigation of the mechanisms underlying atrial fibrillation due to impaired Pitx2
- Bayesian optimization of variable-size design space problems
- Adaptive Boosting (AdaBoost)-based multiwavelength spatial frequency domain imaging and characterization for ex vivo human colorectal tissue assessment
- Testing the efficacy of lionfish traps in the northern Gulf of Mexico
- Detection of CNV in the SH3RF2 gene and its effects on growth and carcass traits in chickens
- Unified Framework for Generalized Statistics: Canonical Partition Function, Maximum Occupation Number, and Permutation Phase of Wave Function
- Deep Bayesian Gaussian processes for uncertainty estimation in electronic health records
- The synergy of damage repair and retention promotes rejuvenation and prolongs healthy lifespans in cell lineages
- An overview on the synthesis and recent applications of conducting poly(3,4-ethylenedioxythiophene) (PEDOT) in industry and biomedicine
- Atmospheric transport is a major pathway of microplastics to remote regions
- Food additive “lauric acid” possess non-toxic profile on biochemical, haematological and histopathological studies in female Sprague Dawley (SD) rats
- The ontogeny of continuous quantity discrimination in zebrafish larvae (Danio rerio)
- Detection of 3,4-diaminotoluene based on Sr0.3Pb0.7TiO3/CoFe2O4 core/shell nanocomposite via an electrochemical approach
- Single-cell transcriptomics combined with interstitial fluid proteomics defines cell-type-specific immune regulation in atopic dermatitis.
- Designing silicon-core fiber tapers for efficient supercontinuum generation in the greenhouse gas absorption region
- Homological scaffold via minimal homology bases
Related papers
- Absence of arylsulphatases A and B in suction blister fluid interstitial fluid and serum
- [Physical bases of blister formation. II. A study of the total osmotic pressure in the blister fluid of suction blisters and of "naturally" occurring blisters as well as in the serum].
- Faster suction blister formation using 2 hair dryers.
- Suction blister fluid as a model for interstitial fluid in rats
- Factors affecting the outcome of the suction blisters using two different harvesting techniques in vitiligo patients
- Developmental expression of human epidermal keratins and filaggrin.
- Peak blistering point: influence on fluid levels of 5-MOP in human skin in vivo after systemic administration
- Suction Device for Epidermal Grafting in Vitiligo: Employing a Syringe and a Manometer to Provide an Adequate Negative Pressure
- Immediate effect of ultraviolet‐B radiation on epidermal lysosomal hydrolases
- Pharmacokinetic studies of antibacterial agents using the suction blister method.