Drug treatment options for the 2019-new coronavirus (2019-nCoV).
Explore this paper's citation graph
Summary
Three general methods, which include existing broad-spectrum antiviral drugs using standard assays, screening of a chemical library containing many existing compounds or databases, and the redevelopment of new specific drugs based on the genome and biophysical understanding of individual coronaviruses, are used to discover the potential antiviral treatment of human pathogen coronavirus.
- Type
- article
- Published
- 2020-01-28
- Cited by
- 1,101
- References
- 23
- Access
- Open access
- OpenAlex
- https://openalex.org/W3003322996
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:210945604
Keywords
Coronavirus, Medicine, Lopinavir, Drug, Antiviral drug
References
- Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings
- Coronaviruses — drug discovery and therapeutic options
- Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor
- Abelson Kinase Inhibitors Are Potent Inhibitors of Severe Acute Respiratory Syndrome Coronavirus and Middle East Respiratory Syndrome Coronavirus Fusion
- The Chinese prescription lianhuaqingwen capsule exerts anti-influenza activity through the inhibition of viral propagation and impacts immune function
- Sex-based differences in susceptibility to SARS-CoV infection
- Treatment of Middle East Respiratory Syndrome with a combination of lopinavir-ritonavir and interferon-β1b (MIRACLE trial): study protocol for a randomized controlled trial
- Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease
- Clinical management of respiratory syndrome in patients hospitalized for suspected Middle East respiratory syndrome coronavirus infection in the Paris area from 2013 to 2016
- A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike
- Unique synergistic antiviral effects of Shufeng Jiedu Capsule and oseltamivir in influenza A viral-induced acute exacerbation of chronic obstructive pulmonary disease.
- Comparative effectiveness of combined favipiravir and oseltamivir therapy versus oseltamivir monotherapy in critically ill patients with influenza virus infection.
- Outbreak of pneumonia of unknown etiology in Wuhan, China: The mystery and the miracle
- Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV
- Report 2: Estimating the potential total number of novel Coronavirus cases in Wuhan City, China
- An overview on COVID-19: reality and expectation
- Focus on a 2019-novel coronavirus (SARS-CoV-2)
- Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2): a global pandemic and treatment strategies
- Natural Products as Potential Leads Against Coronaviruses: Could They be Encouraging Structural Models Against SARS-CoV-2?
- Screening and Druggability Analysis of Some Plant Metabolites Against SARS-CoV-2
Cited by
- Design of a Multiepitope-Based Peptide Vaccine against the E Protein of Human COVID-19: An Immunoinformatics Approach
- Clinical characteristics and therapeutic procedure for four cases with 2019 novel coronavirus pneumonia receiving combined Chinese and Western medicine treatment.
- Emerging novel coronavirus (2019-nCoV)—current scenario, evolutionary perspective based on genome analysis and recent developments
- Wuhan 2019 Novel Coronavirus (2019-nCoV) Pneumonia: A Case Report of Serial Computed Tomographic Findings in a Female Patient (Preprint)
- Emerging threats from zoonotic coronaviruses-from SARS and MERS to 2019-nCoV
- Distribution of the 2019-nCoV Epidemic and Correlation with Population Emigration from Wuhan, China
- An updated estimation of the risk of transmission of the novel coronavirus (2019-nCov)
- Design of multi epitope-based peptide vaccine against E protein of human COVID-19: An immunoinformatics approach
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges
- Fear can be more harmful than the severe acute respiratory syndrome coronavirus 2 in controlling the corona virus disease 2019 epidemic
- Non-invasive respiratory support for patients with novel coronavirus pneumonia: clinical efficacy and reduction in risk of infection transmission
- Designing of a next generation multiepitope based vaccine (MEV) against SARS-COV-2: Immunoinformatics and in silico approaches
- Clinical Characteristics of Imported Cases of COVID-19 in Jiangsu Province: A Multicenter Descriptive Study
- Systematic Comparison of Two Animal-to-Human Transmitted Human Coronaviruses: SARS-CoV-2 and SARS-CoV
- A systematic review of lopinavir therapy for SARS coronavirus and MERS coronavirus—A possible reference for coronavirus disease‐19 treatment option
- Understanding of COVID‐19 based on current evidence
- Dose prediction of lopinavir/ritonavir for 2019-novel coronavirus (2019-nCoV) infection based on mathematic modeling
- 2019 Novel Coronavirus (COVID-19) Pneumonia: Serial Computed Tomography Findings
- Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies.
- The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak
Related papers
- Return of the Coronavirus: 2019-nCoV
- [Determination Methods of 2019 Novel Coronavirus (SARS-CoV-2)].
- Rapid review for the anti-coronavirus effect of remdesivir.
- Research progress on the clinical application of lopinavir/ritonavir for the treatment of coronavirus infection
- Current status of treatment for 2019 novel coronavirus pneumonia
- A rational approach to identifying effective combined anticoronaviral therapies against feline coronavirus
- An Overview on Flavonoids as Potential Antiviral Strategies against Coronavirus Infections