Photo Cross‐Linking Probes Containing ϵ‐N‐Thioacyllysine and ϵ‐N‐Acyl‐(δ‐aza)lysine Residues†
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Summary
This work describes the development of peptide activity/affinity‐based probes for the discovery of proteins that recognize novel acyl‐based PTMs on lysine residues in the proteome, and expects that the technology will have broad future applications for pairing of novel PTMs with the proteins that target them in the cell.
- Type
- article
- Published
- 2020-01-10
- Cited by
- 8
- References
- 92
- Access
- Open access
- OpenAlex
- https://openalex.org/W2999521170
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:210132115
Keywords
Fluorophore, Chemistry, Bioorthogonal chemistry, Peptide, Lysine
References
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- Use of Lawesson's reagent in organic syntheses.
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- Azalysine Analogs as Probes for Protein Lysine Deacetylation and Demethylation
- Acylierung von Lysinen: Erweiterung des Repertoires
- Protein lysine acylation and cysteine succination by intermediates of energy metabolism
Cited by
- Advances and Opportunities in Epigenetic Chemical Biology
- Development of activity-based probes for the protein deacylase Sirt1
- Mitochondria-targeted inhibitors of the human SIRT3 lysine deacetylase
- Flipping the Switch: Innovations in Inducible Probes for Protein Profiling
- Chemical Biology Approaches to Identify and Profile Interactors of Chromatin Modifications
- Chiral Posttranslational Modification to Lysine ε-Amino Groups.
- Photo-Cross-Linking To Delineate Epigenetic Interactome.
- Revealing chromatin-specific functions of histone deacylases.
- Aryl Fluorosulfate Based Inhibitors That Covalently Target the SIRT5 Lysine Deacylase**
- Chemical Biology Tools for Protein Lysine Acylation
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