The Antimicrobial and Immunomodulatory Function of RNase 7 in Skin
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Summary
This review discusses how the characteristics of RNase 7 contribute to innate cutaneous defense and highlight its role in skin infection and inflammation and speculate how a potential dysregulation ofRNase 7 promotes inflammatory skin diseases and if RNase 6 may have therapeutic potential.
- Type
- review
- Published
- 2019-11-05
- Cited by
- 52
- References
- 86
- Access
- Open access
- OpenAlex
- https://openalex.org/W2983449871
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:207759521
Keywords
RNase P, Ribonuclease, Antimicrobial, RNase MRP, Antimicrobial peptides
References
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- Cytokine milieu of atopic dermatitis skin subverts the innate immune response to vaccinia virus.
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- Recombinant Human Eosinophil Cationic Protein
- Ribonuclease 7, an antimicrobial peptide up-regulated during infection, contributes to microbial defense of the human urinary tract
- The eight human “canonical” ribonucleases: Molecular diversity, catalytic properties, and special biological actions of the enzyme proteins
- Angiogenins: a new class of microbicidal proteins involved in innate immunity
- Antimicrobial RNases of human skin.
- Staphylococcus aureus subverts cutaneous defense by d‐alanylation of teichoic acids
- The nature of the principal type 1 interferon-producing cells in human blood.
- Outer Membrane Protein I of Pseudomonas aeruginosa Is a Target of Cationic Antimicrobial Peptide/Protein*
- Skin commensals amplify the innate immune response to pathogens by activation of distinct signaling pathways.
- IL-17A and IFN-γ Synergistically Induce RNase 7 Expression via STAT3 in Primary Keratinocytes
Cited by
- Cutaneous Mycobacterial Infections
- Host Defense Peptide RNase 7 Is Down-regulated in the Skin of Diabetic Patients with or without Chronic Ulcers, and its Expression is Altered with Metformin.
- Antiviral and Immunomodulatory Properties of Antimicrobial Peptides Produced by Human Keratinocytes
- The Human Immune System toward Staphylococcus aureus
- Keratinocytes: innate immune cells in atopic dermatitis
- Tape stripping method is useful for the quantification of antimicrobial peptides on the human skin surface including the stratum corneum
- Human RNase3 immune modulation by catalytic-dependent and independent modes in a macrophage-cell line infection model
- Antimicrobial peptides in patients with anorexia nervosa: comparison with healthy controls and the impact of weight gain
- Host Defence RNases as Antiviral Agents against Enveloped Single Stranded RNA Viruses
- Free human DNA attenuates the activity of antimicrobial peptides in atopic dermatitis
- Antimicrobial peptides and proteins: Interaction with the skin microbiota
- Antimicrobial peptides in hidradenitis suppurativa: a systematic review *
- Recent Advances in the Discovery and Function of Antimicrobial Molecules in Platelets
- Dendritic Hydrogels Induce Immune Modulation in Human Keratinocytes and Effectively Eradicate Bacterial Pathogens
- Gene losses in the common vampire bat illuminate molecular adaptations to blood feeding
- Antimicrobial-wound healing peptides: dual-function molecules for the treatment of skin injuries.
- Structure-Based Design of an RNase Chimera for Antimicrobial Therapy
- Compartmentalized Innate Immune Response of Human Fetal Membranes against Escherichia coli Choriodecidual Infection
- Hydra and the hair follicle – An unconventional comparative biology approach to exploring the human holobiont
- Chemical Barrier Proteins in Human Body Fluids
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