Testing microsatellite instability in solid tumors: the ideal versus what is real.

Keywords

Microsatellite instability, Ideal (ethics), Instability, Microsatellite, Computational biology

References

• Immunohistochemistry versus microsatellite instability testing for screening colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome. Part II. The utility of microsatellite instability testing.Liying Zhang — 2008
• Immunohistochemistry versus microsatellite instability testing for screening colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome. Part I. The utility of immunohistochemistry.Jinru Shia — 2008
• Correction: An Optimized Pentaplex PCR for Detecting DNA Mismatch Repair-Deficient Colorectal CancersAjay Goel, Takeshi Nagasaka, Richard Hamelin — 2010
• The added value of PMS2 immunostaining in the diagnosis of hereditary nonpolyposis colorectal cancerBritta Halvarsson, Annika Lindblom, Eva Rambech — 2006
• Milestones of Lynch syndrome: 1895–2015Henry T. Lynch, Carrie Snyder, Trudy G. Shaw — 2015
• Utility of Immunohistochemistry in Predicting Microsatellite Instability in Endometrial CarcinomaIppolito Modica, Robert A. Soslow, Destin Black — 2007
• Value of pedigree/clinical data, immunohistochemistry and microsatellite instability analyses in reducing the cost of determining hMLH1 and hMSH2 gene mutations in patients with colorectal cancer.Tadeusz Dębniak, Grzegorz Kurzawski, Bohdan Górski — 2000
• Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors.Noralane M. Lindor — 2002
• HIGH COLORECTAL AND LOW ENDOMETRIAL CANCER RISK IN EPCAM DELETION-POSITIVE LYNCH SYNDROME: A COHORT STUDYMarlies Kempers, Roland P. Kuiper, Charlotte W. Ockeloen — 2010
• Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability.Asad Umar, C. Richard Boland, Jonathan P. Terdiman — 2004
• Microsatellite Instability, Immunohistochemistry, and Additional PMS2 Staining in Suspected Hereditary Nonpolyposis Colorectal CancerAndrea E. van der Meulen‐de Jong, Marjo van Puijenbroek, Yvonne Hendriks — 2004
• Multipopulation analysis of polymorphisms in five mononucleotide repeats used to determine the microsatellite instability status of human tumors.Olivier Buhard, Francesca Cattaneo, Yick Fu Wong — 2006
• Mismatch repair status and BRAF mutation status in metastatic colorectal cancer patients: a pooled analysis of the CAIRO, CAIRO2, COIN and FOCUS studiesSabine Venderbosch, Irıs D. Nagtegaal, Tim Maughan — 2014
• Accuracy of revised Bethesda guidelines, microsatellite instability, and immunohistochemistry for the identification of patients with hereditary nonpolyposis colorectal cancer.Virgı́nia Piñol — 2005
• Microsatellite Instability as a Biomarker for PD-1 BlockadeJonathan C. Dudley, Ming‐Tseh Lin, Dung T. Le — 2016
• The evolving role of microsatellite instability in colorectal cancer: A review.Fabio Gelsomino, Monica Barbolini, Andrea Spallanzani — 2016
• Immunohistochemistry for Pathologists: Protocols, Pitfalls, and TipsSo‐Woon Kim, Jin Roh, Chan-Sik Park — 2016
• PD-1 blockade in tumors with mismatch repair deficiency.Dung T. Le, Jennifer N. Uram, Hao Wang — 2015
• Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burdenZachary R. Chalmers, Caitlin Connelly, David Fabrizio — 2017
• Financial toxicity and implications for cancer care in the era of molecular and immune therapies.George Tran, S. Yousuf Zafar — 2018

Cited by

• Immunotherapy in Metastatic Colorectal Cancer: Could the Latest Developments Hold the Key to Improving Patient Survival?Emmanouil Damilakis, Dimitrios Mavroudis, Maria Sfakianaki — 2020
• Treatment patterns and real-world clinical outcomes in patients with advanced endometrial cancer that are non-microsatellite instability high (non-MSI-high) or mismatch repair proficient (pMMR) in the United StatesSneha S. Kelkar, Vimalanand S. Prabhu, Jingchuan Zhang — 2022
• High concordance rate of capillary electrophoresis workflow for microsatellite instability analysis and mismatch repair (MMR) immunostaining in colorectal carcinomaWenya Huang, Chung‐Liang Ho, Chung‐Ta Lee — 2023
• Microsatellite Instability Detection: The Current Standards, Limitations, and Misinterpretations.V. D. Yakushina, Alexandra Kavun, Egor Veselovsky — 2023
• Current Status of the Diagnosis and Treatment of Mismatch Repair Deficient Colorectal CancerDonald Bastin, Vladimir Djedovic, Angela Hyde — 2026

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