Curcumin protects the pancreas from acute pancreatitis via the mitogen-activated protein kinase signaling pathway
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Summary
Curcumin may lower the severity and inflammatory response via the mitogen-activated protein kinase-signaling pathway, to some extent, and future studies are required to fully understand the protective effects of curcumin on AP.
- Type
- article
- Published
- 2019-08-01
- Cited by
- 28
- References
- 31
- Access
- Open access
- OpenAlex
- https://openalex.org/W2965744493
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:201116327
Keywords
Curcumin, Acute pancreatitis, Protein kinase A, Viability assay, Tumor necrosis factor alpha
References
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- Curcumin Mediates a Protective Effect Via TLR-4/NF-κB Signaling Pathway in Rat Model of Severe Acute Pancreatitis
- Increased expression of the intercellular adhesion molecule-1 (ICAM-1) on peripheral blood neutrophils in acute pancreatitis.
- Protective effect of curcumin against liver warm ischemia/reperfusion injury in rat model is associated with regulation of heat shock protein and antioxidant enzymes.
- Azithromycin modulates neutrophil function and circulating inflammatory mediators in healthy human subjects.
- In vitro evidence for role of ERK, p38, and JNK in exocrine pancreatic cytokine production
- Compartmentalization of the inflammatory response during acute pancreatitis: correlation with local and systemic complications.
- Baseline Hypoxemia as a Prognostic Marker for Pulmonary Complications and Outcome in Patients with Acute Pancreatitis
- The Role of p38 MAPK in Neutrophil Functions: Single Cell Chemotaxis and Surface Marker Expression
- PTEN/MAPK pathways play a key role in platelet‐activating factor‐induced experimental pulmonary tumor metastasis
- Curcumin Inhibits Tumor Growth and Angiogenesis in an Orthotopic Mouse Model of Human Pancreatic Cancer
- Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research.
- Acute Pancreatitis in Chronic Kidney Disease—A Common but Often Misunderstood Combination
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- Effects of curcumin on tumour necrosis factor-alpha and interleukin-6 in the late phase of experimental acute pancreatitis.
Cited by
- Kaempferol, kurkumin ve kaempferol-kurkumin kombinasyonunun deneysel akut pankreatitteki etkileri
- Knockdown of interferon-induced transmembrane protein 1 inhibited proliferation, induced cell cycle arrest and apoptosis, and suppressed MAPK signaling pathway in pancreatic cancer cells
- The Power of Phytochemicals Combination in Cancer Chemoprevention
- Cinnamic acid nanoparticles modulate redox signal and inflammatory response in gamma irradiated rats suffering from acute pancreatitis.
- Borneol protects against cerulein‐induced oxidative stress and inflammation in acute pancreatitis mice model
- Updated Review on the Role of Curcumin in Gastrointestinal Cancers.
- Antioxidant Therapy in Pancreatitis
- Phytochemicals with protective effects against acute pancreatitis: a review of recent literature
- Targeting Endoplasmic Reticulum Stress as an Effective Treatment for Alcoholic Pancreatitis
- Uncovering the Pharmacological of Xiaochaihu Decoction in the Treatment of Pancreatitis Based on the Network Pharmacology
- Relationship Between the In Vitro Efficacy, Pharmacokinetics and In Vivo Efficacy of Curcumin.
- Phenolic Phytochemicals for Prevention and Treatment of Colorectal Cancer: A Critical Evaluation of In Vivo Studies
- Dynamic Contrast-Enhanced MRI Assessing Antifibrotic Therapeutic Effects of Pancreatic Fibrosis with Curcumin - An Experimental Study at 11.7 T.
- Nano‐curcumin supplementation in patients with mild and moderate acute pancreatitis: A randomized, placebo‐controlled trial
- Natural Compounds for the Treatment of Acute Pancreatitis: Novel Anti-Inflammatory Therapies
- Natural Antioxidants: New Possibilities For The Treatment and Prevention of Acute Pancreatitis
- Potential of curcumin and its derivatives, modern insights on the anticancer properties: a comprehensive overview
- Curcumin ameliorates cerulein‑induced chronic pancreatitis through Nrf‑2/HO‑1 signaling
- Targeting the gut microbiome dynamics and treatment strategies in acute pancreatitis
- Targeting Oxidative Stress in Acute Pancreatitis: A Critical Review of Antioxidant Strategies
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