Dephosphorylation of clustered phosphoserine residues in human Grb14 by protein phosphatase 1 and its effect on insulin receptor complex formation

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Summary

Phosphatase‐mediated dephosphorylation of the hGrb14 phosphoserine residues is investigated, and it is suggested that phosphate groups on Ser358 and Ser362 in h Grb14 are de phosphorylated by PP1, and the deph phosphorylation facilitates hGrB14–IR complex formation.

Type
article
Published
2019-07-25
Cited by
1
References
29

Keywords

Phosphoserine, Dephosphorylation, Chemistry, Insulin receptor, DUSP6

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