Cancer Cell Lines Are Useful Model Systems for Medical Research
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Summary
Comparing genomic data of most cancer cell lines has corroborated this statement and those that were observed studying the tumoral tissue equivalents included in the The Cancer Genome Atlas (TCGA) database are corroborated.
- Type
- review
- Published
- 2019-08-01
- Cited by
- 285
- References
- 97
- Access
- Open access
- OpenAlex
- https://openalex.org/W2965206386
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:199388877
Keywords
Cancer, Cancer cell lines, Cell culture, Computational biology, Cancer cell
References
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- Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents.
- The Cancer Genome Atlas Pan-Cancer Analysis Project
- NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3).
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- Henrietta Lacks, HeLa cells, and cell culture contamination.
- Drug discovery: Cell lines battle cancer
- Cross-contamination of cells in culture.
- Guidelines for the use of cell lines in biomedical research
- Malignant hematopoietic cell lines: in vitro models for the study of Waldenström's macroglobulinemia.
- A comprehensive transcriptional portrait of human cancer cell lines
- Leukemia cell lines: in vitro models for the study of chronic myeloid leukemia.
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- Common and Differential Traits of the Membrane Lipidome of Colon Cancer Cell Lines and Their Secreted Vesicles: Impact on Studies Using Cell Lines
- Establishment and characterization of a novel ‘double‐hit’ follicular lymphoma cell line, FL‐SJC
- KCTD15 Protein Expression in Peripheral Blood and Acute Myeloid Leukemia
- The LL-100 Cell Lines Panel: Tool for Molecular Leukemia–Lymphoma Research
- A double-Flp-in method for stable overexpression of two genes
- miR-34c-3p targets CDK1 a synthetic lethality partner of KRAS in non-small cell lung cancer
- Cryo-nanoscale chromosome imaging—future prospects
- Modeling cancer progression using human pluripotent stem cell-derived cells and organoids
- Mass Spectrometry-Based Cellular Metabolomics: Current Approaches, Applications, and Future Directions.
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- Curcumin against Prostate Cancer: Current Evidence
- Cholangiocarcinoma: Bridging the translational gap from preclinical to clinical development and implications for future therapy.
- Potential impact of tissue molecular heterogeneity on ambient mass spectrometry profiles: a note of caution in choosing the right disease model
- Identification of Tamoxifen-Resistant Breast Cancer Cell Lines and Drug Response Signature
- Design, Synthesis and Molecular Docking of Chalcone Derivatives as Potential Anticancer Agents
- Oxidative Pentose Phosphate Pathway Enzyme 6-Phosphogluconate Dehydrogenase Plays a Key Role in Breast Cancer Metabolism
- Transcriptionally active enhancers in human cancer cells
- Nanotoxic Effects of Silver Nanoparticles on Normal HEK-293 Cells in Comparison to Cancerous HeLa Cell Line
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