pDC Activation by TLR7/8 Ligand CL097 Compared to TLR7 Ligand IMQ or TLR9 Ligand CpG
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Summary
The size of pDCs increased significantly after activation by TLR7, orTLR7/8 ligands, and Interestingly, TLR6/8 and CL097 ligands induced stronger responses, which may aid in the development of a new strategy for future tumor immunotherapy.
- Type
- article
- Published
- 2019-04-09
- Cited by
- 24
- References
- 29
- Access
- Open access
- OpenAlex
- https://openalex.org/W2938746831
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:145905540
Keywords
TLR7, TLR9, Ligand (biochemistry), Imiquimod, Receptor
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Cited by
- Intratumoral CpG-B Promotes Antitumoral Neutrophil, cDC, and T-cell Cooperation without Reprograming Tolerogenic pDC.
- TLR9-Activating CpG-B ODN but Not TLR7 Agonists Triggers Antibody Formation to Factor IX in Muscle Gene Transfer
- Plasmacytoid dendritic cells regulate colitis-associated tumorigenesis by controlling myeloid-derived suppressor cell infiltration.
- Application of imiquimod-induced murine psoriasis model in evaluating interleukin-17A antagonist
- Monogenic autoimmunity caused by TLR7 gain-of-function
- The transcription factor reservoir and chromatin landscape in activated plasmacytoid dendritic cells
- The Signal Peptide and Chaperone UNC93B1 Both Influence TLR8 Ectodomain Intracellular Endosomal Localization
- The Critical Role of Toll-like Receptor-mediated Signaling in Cancer Immunotherapy
- TLR7 gain-of-function genetic variation causes human lupus
- Type 1 interferon mediated signaling is indispensable for eliciting anti-tumor responses by Mycobacterium indicus pranii
- NET-targeted therapy: effects, limitations, and potential strategies to enhance treatment efficacy.
- Toll-Like Receptors 7/8: A Paradigm for the Manipulation of Immunologic Reactions for Immunotherapy
- Association of TLR8 Variants in Sex-Based Clinical Differences in Patients with COVID-19
- Defective endomembrane dynamics in Rab27a deficiency impairs nucleic acid sensing and cytokine secretion in immune cells
- Nuclear scaffold attachment factor A functions as a potential viral recognition receptor involved in the antiviral immunity of grass carp (Ctenopharyngodon idella).
- Exploring TLR agonists as adjuvants for COVID-19 oral vaccines.
- Divergent functions of TLRs in gastrointestinal (GI) cancer: Overview of their diagnostic, prognostic and therapeutic value.
- The synapse revisited: Molecular networks of CD4 T cell-DC interactions.
- The transcription factor reservoir and chromatin landscape in activated plasmacytoid dendritic cells
- Anti-Psoriatic Effects of J2H-1802, a Mycophenolate Mofetil and 5-Aminosalicylic Acid Hybrid, in an Imiquimod-Induced Psoriasis-like Mouse Model
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