The isolated C-terminal nuclear localization sequence of the breast cancer metastasis suppressor 1 is disordered
Explore this paper's citation graph
Summary
It is suggested that NLS2 is a disordered region, with non pre-formed structure, that participates in metastasis suppression.
- Type
- article
- Published
- 2019-01-30
- Cited by
- 10
- References
- 51
- Access
- Open access
- OpenAlex
- https://openalex.org/W2911708774
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:73414103
Keywords
Circular dichroism, Random coil, Molecular dynamics, Sequence (biology), Nuclear localization sequence
References
- BRMS151-98 and BRMS151-84 are crystal oligomeric coiled coils with different oligomerization states, which behave as disordered protein fragments in solution.
- Fatty acid binding into the highest affinity site of human serum albumin observed in molecular dynamics simulation.
- GROMACS: High performance molecular simulations through multi-level parallelism from laptops to supercomputers
- Water dispersion interactions strongly influence simulated structural properties of disordered protein states.
- Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions
- Comparison of simple potential functions for simulating liquid water
- Unraveling the enigmatic complexities of BRMS1-mediated metastasis suppression
- The structure of BRMS1 nuclear export signal and SNX6 interacting region reveals a hexamer formed by antiparallel coiled coils.
- Sequence-dependent correction of random coil NMR chemical shifts.
- Calculation of protein extinction coefficients from amino acid sequence data.
- Rules for nuclear localization sequence recognition by karyopherin beta 2.
- Protein secondary structure analyses from circular dichroism spectroscopy: methods and reference databases.
- VMD: visual molecular dynamics.
- Translational diffusion measured by PFG‐NMR on full length and fragments of the Alzheimer Aβ(1–40) peptide. Determination of hydrodynamic radii of random coil peptides of varying length
- The C-Terminal Putative Nuclear Localization Sequence of BReast cancer Metastasis Suppressor 1, BRMS1, Is Necessary for Metastasis Suppression
- A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules.
- Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha.
- Atomic resolution structures in nuclear transport.
- Practical aspects of two-dimensional transverse NOE spectroscopy
- Building Water Models: A Different Approach
Cited by
- The Peptide ERα17p Is a GPER Inverse Agonist that Exerts Antiproliferative Effects in Breast Cancer Cells
- Dynamics of the intrinsically disordered inhibitor IF7 of glutamine synthetase in isolation and in complex with its partner.
- The chromogranin A1‐373 fragment reveals how a single change in the protein sequence exerts strong cardioregulatory effects by engaging neuropilin‐1
- Residues flanking the ARKme3T/S motif allow binding of diverse targets to the HP1 chromodomain: Insights from molecular dynamics simulations.
- Perturbation of BRMS1 interactome reveals pathways that impact cell migration
- Perturbation of BRMS1 interactome reveals pathways that impact metastasis
- Magnesium Force Fields for OPC Water with Accurate Solvation, Ion-Binding, and Water-Exchange Properties: Successful Transfer from SPC/E
- Molecular simulations of proteins: From simplified physical interactions to complex biological phenomena.
- Deciphering the Binding of the Nuclear Localization Sequence of Myc Protein to the Nuclear Carrier Importin α3
Related papers
- [Effect of pH on circular dichroism and Raman spectroscopy of secondary structure of beta-casein from Chinese human milk].
- Structural plasticity of the feline leukaemia virus fusion peptide: a circular dichroism study
- Circular Dichroism Spectra and Secondary Structures in Solution of Flammulin
- Effect of vacuum treatment on secondary structure of superoxide dismutase investigated by circular dichroism spectrum
- Silver‐induced conformational changes of polypeptides: a CD study
- Solution conformation of tuftsin.
- Influence of enzyme conformational changes on catalytic activity investigated by circular dichroism spectroscopy
- Spectroscopic and functional characterization of human beta-synuclein.
- Thermal denaturation of a recombinant mouse amelogenin: Circular dichroism and differential scanning calorimetric studies