Genetic Analyses of Alzheimer's Disease in China: Achievements and Perspectives.
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Summary
An overview of the current state of AD genetic research in China is presented, with an emphasis on genome-level studies, and the challenges and opportunities for future advances are described.
- Type
- review
- Published
- 2019-01-30
- Cited by
- 26
- References
- 89
- OpenAlex
- https://openalex.org/W2911402208
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:59411403
Keywords
Disease, Genome-wide association study, Genetic association, Biology, Candidate gene
References
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- Cruchaga & Goate reply
- Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
- China’s Demographic History and Future Challenges
Cited by
- Mutation and association analyses of dementia-causal genes in Han Chinese patients with early-onset and familial Alzheimer's disease.
- Physiological and pathological insights into exosomes in the brain
- Association of Genes Involved in the Metabolic Pathways of Amyloid-β and Tau Proteins With Sporadic Late-Onset Alzheimer’s Disease in the Southern Han Chinese Population
- Exploring the Genetic Association of the ABAT Gene with Alzheimer’s Disease
- Evaluation of the prevention and treatment effects of acupuncture-moxibustion for Alzheimer disease based on various mouse models
- Association between Alzheimer’s disease genes and trajectories of cognitive function decline in Han Chinese in Taiwan
- A novel missense variant in ACAA1 contributes to early-onset Alzheimer’s disease, impairs lysosomal function, and facilitates amyloid-β pathology and cognitive decline
- Genetic mutations of APOEε4 carriers in cardiovascular patients lead to the development of insulin resistance and risk of Alzheimer's disease
- Fluorescent detection of copper ions with acylhydrazine-based probes: Effects of substitute and its position
- Design, Synthesis and Biological Evaluation of New 3,4-Dihydro-2(1H)-Quinolinone-Dithiocarbamate Derivatives as Multifunctional Agents for the Treatment of Alzheimer’s Disease
- Bridging Integrator 1 (BIN1, rs6733839) and Sex Are Moderators of Vascular Health Predictions of Memory Aging Trajectories
- CX3CL1 Derived from Bone Marrow Mesenchymal Stem Cells Inhibits Aβ1-42-Induced SH-SY5Y Cell Pathological Damage through TXNIP/NLRP3 Signaling Pathway
- The associations of APP , PSEN1 , and PSEN2 genes with Alzheimer's disease: A large case–control study in Chinese population
- Overexpression of fibroblast growth factor 13 ameliorates amyloid-β-induced neuronal damage
- A novel promising neuroprotective agent: Ganoderma lucidum polysaccharide.
- A novel colorimetric and ratiometric fluorescent probe for detection of Cu2+ with large Stokes shift in complete aqueous solution
- Functional genomics identify causal variant underlying the protective CTSH locus for Alzheimer’s disease
- Neuroprotective Effects of Phenolic Antioxidant Tert-butylhydroquinone (tBHQ) in Brain Diseases
- RIPK2 inhibitors for disease therapy: Current status and perspectives.
- Dual engine-driven bionic microneedles for early intervention and prolonged treatment of Alzheimer's disease.
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