HIPPO signaling resolves embryonic cell fate conflicts during establishment of pluripotency in vivo
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- Type
- preprint
- Published
- 2018-05-08
- Cited by
- 5
- References
- 66
- Access
- Open access
- OpenAlex
- https://openalex.org/W2903854672
Keywords
YAP1, Hippo signaling pathway, SOX2, Cell fate determination, Cell biology
References
- Noninvasive visualization of molecular events in the mammalian zygote
- Pulsatile cell-autonomous contractility drives compaction in the mouse embryo
- Cortical Tension Allocates the First Inner Cells of the Mammalian Embryo.
- Tight junction assembly during mouse blastocyst formation is regulated by late expression of ZO-1 alpha+ isoform.
- Par‐aPKC‐dependent and ‐independent mechanisms cooperatively control cell polarity, Hippo signaling, and cell positioning in 16‐cell stage mouse embryos
- Downregulation of Par3 and aPKC function directs cells towards the ICM in the preimplantation mouse embryo
- Gata3 regulates trophoblast development downstream of Tead4 and in parallel to Cdx2
- Angiomotin prevents pluripotent lineage differentiation in mouse embryos via Hippo pathway-dependent and -independent mechanisms
- Notch and Hippo converge on Cdx2 to specify the trophectoderm lineage in the mouse blastocyst
- Inhibition of RHO-ROCK signaling enhances ICM and suppresses TE characteristics through activation of Hippo signaling in the mouse blastocyst
- Defects in Yolk Sac Vasculogenesis, Chorioallantoic Fusion, and Embryonic Axis Elongation in Mice with Targeted Disruption of Yap65
- Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
- Asymmetric distribution of PAR proteins in the mouse embryo begins at the 8-cell stage during compaction.
- Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst
- Generation and Live Imaging of an Endogenous Cdx2 Reporter Mouse Line
- Expression and distribution of cell adhesion molecule uvomorulin in mouse preimplantation embryos.
- The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass.
- Oct-4 transcription factor is differentially expressed in the mouse embryo during establishment of the first two extraembryonic cell lineages involved in implantation.
- The role of angiomotin phosphorylation in the Hippo pathway during preimplantation mouse development
- Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos.
Cited by
- RHOA activity in expanding blastocysts is essential to regulate HIPPO-YAP signaling and to maintain the trophectoderm-specific gene expression program in a ROCK/actin filament-independent manner
- Maternal Yes-Associated Protein Participates in Porcine Blastocyst Development via Modulation of Trophectoderm Epithelium Barrier Function
- Identification of a Goat Intersexuality-Associated Novel Variant Through Genome-Wide Resequencing and Hi-C
- Building Pluripotency Identity in the Early Embryo and Derived Stem Cells
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