The Appropriateness of Testing Platelet Factor 4/Heparin Antibody in Patients Suspected of Heparin-induced Thrombocytopenia
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Summary
The large majority of patients were not appropriately evaluated prior to testing, which incurred unnecessary expense and patient distress, and for the proper identification of patients suspected of HIT who should undergo PF4/heparin antibody testing, further education of the ordering physicians is recommended.
- Type
- article
- Published
- 2018-10-01
- Cited by
- 2
- References
- 11
- Access
- Open access
- OpenAlex
- https://openalex.org/W2898699118
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:58008884
Keywords
Heparin-induced thrombocytopenia, Medicine, Platelet factor 4, Heparin, Intensive care unit
References
- Predictive value of the 4Ts scoring system for heparin-induced thrombocytopenia: a systematic review and meta-analysis.
- Characterisation of the conformational changes in platelet factor 4 induced by polyanions: towards in vitro prediction of antigenicity
- Timely diagnosis and management of heparin‐induced thrombocytopenia in a frequent request, low incidence single centre using clinical 4T’s score and particle gel immunoassay
- Arterial embolism occurring during systemic heparin therapy.
- Quantitative interpretation of optical density measurements using PF4‐dependent enzyme‐immunoassays
- How I diagnose and manage HIT.
- Evaluation of pretest clinical score (4 T's) for the diagnosis of heparin‐induced thrombocytopenia in two clinical settings
- Defining an antigenic epitope on platelet factor 4 associated with heparin-induced thrombocytopenia.
- When heparins promote thrombosis: review of heparin-induced thrombocytopenia.
- Heparin-induced immune thrombocytopenia.
- Heparin induced thrombocytopenia with thrombotic and hemorrhagic manifestations.
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