Prior Knowledge Driven Joint NMF Algorithm for ceRNA Co-Module Identification

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Summary

The joint matrix factorization method integrating prior knowledge is developed to map the three types of RNA data of lung cancer to the common coordinate system and construct the ceRNA network corresponding to thecommon module, showing that more than 90% of the modules are closely related to cancer, including lung cancer.

Type
article
Published
2018-10-19
Cited by
17
References
51
Access
Open access

Keywords

Competing endogenous RNA, microRNA, Computational biology, Biology, Construct (python library)

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