Role of fibroblast growth factor 21 in gestational diabetes mellitus: A mini‐review
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Summary
GDM and T2DM are proposed to have similar underlying pathophysiologies, raising the question of whether a similar relationship exists between FGF21 and GDM as it does with T2 DM.
- Type
- review
- Published
- 2018-11-15
- Cited by
- 23
- References
- 64
- Access
- Open access
- OpenAlex
- https://openalex.org/W2896225808
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:53041965
Keywords
FGF21, Endocrinology, Internal medicine, Gestational diabetes, Diabetes mellitus
References
- Gestational diabetes and insulin resistance: role in short- and long-term implications for mother and fetus.
- Fibroblast growth factors in cardiovascular disease: The emerging role of FGF21.
- Diagnostic criteria and classification of hyperglycaemia first detected in pregnancy: a World Health Organization Guideline.
- FGF21 as a therapeutic reagent.
- Research Design and Methods
- Plasma FGF21 displays a circadian rhythm during a 72‐h fast in healthy female volunteers
- Cellular mechanisms by which FGF21 improves insulin sensitivity in male mice.
- Cord blood FGF21 in gestational diabetes and its relationship with postnatal growth
- The circulating metabolic regulator FGF21 is induced by prolonged fasting and PPARalpha activation in man.
- Secretion of adiponectin by human placenta: differential modulation of adiponectin and its receptors by cytokines
- Hepatic FGF21 Expression Is Induced at Birth via PPARα in Response to Milk Intake and Contributes to Thermogenic Activation of Neonatal Brown Fat
- Identification of a novel FGF, FGF-21, preferentially expressed in the liver.
- FGF-21 as a novel metabolic regulator.
- FGF21 attenuates lipolysis in human adipocytes – A possible link to improved insulin sensitivity
- Long-term fenofibrate therapy increases fibroblast growth factor 21 and retinol-binding protein 4 in subjects with type 2 diabetes.
- A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway.
- Inhibition of lipolysis may contribute to the acute regulation of plasma FFA and glucose by FGF21 in ob/ob mice
- Development of a Novel Long-Acting Antidiabetic FGF21 Mimetic by Targeted Conjugation to a Scaffold Antibody
- Elevated Plasma SPARC Levels Are Associated with Insulin Resistance, Dyslipidemia, and Inflammation in Gestational Diabetes Mellitus
- Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis.
Cited by
- Fibroblast growth factor 21: A role in cardiometabolic disorders and cardiovascular risk prediction?
- The blood proteomic signature of early-onset pediatric atopic dermatitis shows systemic inflammation and is distinct from adult long-standing disease.
- A Recent Achievement In the Discovery and Development of Novel Targets for the Treatment of Type-2 Diabetes Mellitus
- Fibroblast Growth Factor 21 is Related to Atherosclerosis Independent of Nonalcoholic Fatty Liver Disease and Predicts Atherosclerotic Cardiovascular Events
- Fibroblast Growth Factor 21 and Metabolic Dysfunction in Women with a Prior Glucose-Intolerant Pregnancy
- Identification of metabolic markers predictive of prediabetes in a Korean population
- Influence of ursodeoxycholic acid therapy on levels of fibroblast growth factor 21, adiponectin and biochemical parameters in intrahepatic cholestasis of pregnancy
- Oestrogen receptor α in T cells controls the T cell immune profile and glucose metabolism in mouse models of gestational diabetes mellitus
- Pathophysiology and risk factors of peripartum cardiomyopathy
- Maternal Fibroblast Growth Factor 21 Levels Decrease during Early Pregnancy in Normotensive Pregnant Women but Are Higher in Preeclamptic Women—A Longitudinal Study
- Fibroblast Growth Factor 21 Levels and Bone Mineral Density in Metabolically Healthy and Metabolically Unhealthy Obese Children
- The relationship between serum adipokine fibroblast growth factor‐21 and gestational diabetes mellitus
- The CEBPA-FGF21 regulatory network may participate in the T2DM-induced skeletal muscle atrophy by regulating the autophagy-lysosomal pathway
- Maternal overweight and obesity modify the association of serum fibroblast growth factor 21 levels with gestational diabetes mellitus: A nested case‐control study
- Elevated serum FGF21 is an independent predictor for adverse events in hemodialysis patients from two large centers: a prospective cohort study
- Fibroblast Growth Factor 21 in Gestational Diabetes Mellitus and Type 2 Diabetes Mellitus
- ROLE OF MATERNAL SERUM FIBROBLAST GROWTH FACTOR 21 LEVEL IN PREDICTION OF PREECLAMPSIA
- Impact of various dietary lipids on amelioration of biomarkers linked to metabolic syndrome in both healthy and diabetic Wistar rats
- Beyond Metabolism; Fibroblast Growth Factor-21; A New Frontier in Women’s Health and Reproduction
- Transcriptomic analysis reveals potential biomarkers for early-onset pre-eclampsia using integrative bioinformatics and LASSO based approach
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