Mitochondrial Morphofunction in Mammalian Cells
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Summary
This review discusses the concept of mitochondrial morphofunction in mammalian cells, primarily using experimental evidence obtained within the last decade and summarizes in detail how mitochondrial (ultra)structure is controlled and discusses empirical evidence regarding the equivalence of mitochondrial (ultra)structure and function.
- Type
- review
- Published
- 2019-05-03
- Cited by
- 91
- References
- 475
- Access
- Open access
- OpenAlex
- https://openalex.org/W2894188334
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:52881773
Keywords
Mitochondrion, Biology, Cell biology, mitochondrial fusion, Function (biology)
References
- Mitochondria are morphologically heterogeneous within cells
- Structure of dimeric mitochondrial ATP synthase: novel F0 bridging features and the structural basis of mitochondrial cristae biogenesis.
- Mitofusins and OPA1 mediate sequential steps in mitochondrial membrane fusion.
- Forward operation of adenine nucleotide translocase during F0F1‐ATPase reversal: critical role of matrix substrate‐level phosphorylation
- High glucose induces mitochondrial morphology and metabolic changes in retinal pericytes.
- Adapt and Divide: The Emerging Importance of Dynamin Adaptors in Mitochondrial Fission
- Regulation of Mitochondrial Morphology by Lipids
- Usage of a Localised Microflow Device to Show that Mitochondrial Networks Are Not Extensive in Skeletal Muscle Fibres
- Crystal structure and functional analysis of MiD49, a receptor for the mitochondrial fission protein Drp1
- Super-resolution imaging for cell biologists: concepts, applications, current challenges and developments.
- Visualization and quantification of mitochondrial dynamics in living animal cells.
- Division of Mitochondria in Cultured Human Fibroblasts
- Role of an energized inner membrane in mitochondrial protein import. Delta psi drives the movement of presequences.
- Redox Homeostasis and Mitochondrial Dynamics.
- Mitochondrial complex I assembly: an exploration in the living cell
- Photoactivatable green fluorescent protein-based visualization and quantification of mitochondrial fusion and mitochondrial network complexity in living cells
- Inhibitors of Mitochondrial Fission as a Therapeutic Strategy for Diseases with Oxidative Stress and Mitochondrial Dysfunction
- The Opa1-Dependent Mitochondrial Cristae Remodeling Pathway Controls Atrophic, Apoptotic, and Ischemic Tissue Damage
- Antioxidants in Translational Medicine
- Redox Modulation by Reversal of the Mitochondrial Nicotinamide Nucleotide Transhydrogenase.
Cited by
- Mitofusins modulate the increase in mitochondrial length, bioenergetics and secretory phenotype in therapy-induced senescent melanoma cells
- Mitochondrial Mass Assessment in a Selected Cell Line under Different Metabolic Conditions
- The spatio-temporal organization of mitochondrial F1FO ATP synthase in cristae depends on its activity mode.
- Visualization of mitochondrial membrane potential in mammalian cells.
- Mitochondrial Dysfunction and Ovarian Aging.
- Variants in NGLY1 lead to intellectual disability, myoclonus epilepsy, sensorimotor axonal polyneuropathy and mitochondrial dysfunction
- Fibroblast mitochondria in idiopathic Parkinson’s disease display morphological changes and enhanced resistance to depolarization
- Cadmium elicits alterations in mitochondrial morphology and functionality in C3H10T1/2Cl8 mouse embryonic fibroblasts.
- Conditional knockout of pyruvate dehydrogenase in mouse pancreatic β-cells causes morphological and functional changes
- Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
- Mitochondrial Bioenergetics and Dynamics in Secretion Processes
- The essential functions of mitochondrial dynamics in immune cells
- Cardiac complications in inherited mitochondrial diseases
- Targeting Mitochondrial Complex I Overcomes Chemoresistance in High OXPHOS Pancreatic Cancer
- Mitochondria-targeted phenolic antioxidants induce ROS-protective pathways in primary human skin fibroblasts.
- Advances in mt-tRNA Mutation-Caused Mitochondrial Disease Modeling: Patients’ Brain in a Dish
- Vacuole and Mitochondria Patch (vCLAMP) Protein Vam6 Is Involved in Maintenance of Mitochondrial and Vacuolar Functions under Oxidative Stress in Candida albicans
- The Effect of Acute Aerobic Exercise on Redox Homeostasis and Mitochondrial Function of Rat White Adipose Tissue
- Reimagining dots and dashes: visualizing structure and function of organelles for high-content imaging analysis
- 3D neuronal mitochondrial morphology in axons, dendrites, and somata of the aging mouse hippocampus
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