Mechanisms of Insulin Action and Insulin Resistance.
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Summary
This work aims to develop an integrated physiological perspective, placing the intricate signaling effectors that carry out the cell-autonomous response to insulin in the context of the tissue-specific functions that generate the coordinated organismal response.
- Type
- review
- Published
- 2018-10-01
- Cited by
- 2,487
- References
- 980
- Access
- Open access
- OpenAlex
- https://openalex.org/W2886865853
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:51887525
Keywords
Insulin resistance, Insulin, Adipose tissue, Biology, Insulin receptor
References
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- Molecular adaptations in human subcutaneous adipose tissue after ten weeks of endurance exercise training in healthy males.
- Relation of the degree of obesity in childhood to adipose tissue insulin resistance
- Insulin and Insulin Receptors in Adipose Tissue Development
- Emerging awareness on the importance of skeletal muscle in liver diseases: time to dig deeper into mechanisms!
- PGC1A regulates the IRS1:IRS2 ratio during fasting to influence hepatic metabolism downstream of insulin
- Sphingolipid Metabolism: New Insight into Ceramide-Induced Lipotoxicity in Muscle Cells
- Muscle Insulin Resistance and the Inflamed Microvasculature: Fire from Within
- Paternal high‐fat diet transgenerationally impacts hepatic immunometabolism
- Amino acids at the intersection of nutrition and insulin sensitivity.
- Antidiabetic Properties of Naringenin: A Citrus Fruit Polyphenol
- The effects of green tea on lipid metabolism and its potential applications for obesity and related metabolic disorders - An existing update.
- Tissue-specific insulin sensitivity in humans - with special reference to the liver
- PID1 regulates insulin-dependent glucose uptake by controlling intracellular sorting of GLUT4-storage vesicles
- Endoplasmic Reticulum Stress: A Critical Molecular Driver of Endothelial Dysfunction and Cardiovascular Disturbances Associated with Diabetes
- The incretin system in healthy humans: The role of GIP and GLP-1.
- Insulin resistance: Impact on therapeutic developments in diabetes
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