The unusual flagellar-targeting mechanism and functions of the trypanosome ortholog of the ciliary GTPase Arl13b
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Summary
The identification and characterized Trypanosoma brucei (Tb)Arl13, the sole Arl13b homolog in this evolutionarily divergent, protozoan parasite, and the finding that flagellar enrichment is crucial for TbArl 13 extend the understanding of the roles of Arl12b and Arl 13b–Arl3 pathway in a divergent flageLLate of medical importance.
- Type
- article
- Published
- 2018-09-01
- Cited by
- 9
- References
- 101
- Access
- Open access
- OpenAlex
- https://openalex.org/W2886647509
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:51957953
Keywords
Biology, GTPase, Cell biology, Axoneme, Guanine nucleotide exchange factor
References
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Cited by
- Flagellar targeting of an arginine kinase requires a conserved lipidated protein intraflagellar transport (LIFT) pathway in Trypanosoma brucei
- Basal Body Protein TbSAF1 Is Required for Microtubule Quartet Anchorage to the Basal Bodies in Trypanosoma brucei
- Unanticipated diversity, undiscovered ancient paralogs, and Asgard origins of the ARF GTPase protein family
- A Eukaryote-Wide Perspective on the Diversity and Evolution of the ARF GTPase Protein Family
- First person – Yiliu (Charlie) Zhang
- Arl3 regulates ODA16-mediated intraflagellar transport in motile cilia biogenesis
- ARL3 GTPases facilitate ODA16 unloading from IFT in motile cilia
- Proteins with proximal-distal asymmetries in axoneme localisation control flagellum beat frequency
- Spatial regulation of ARL3 and GSF‐mediated lipidated cargo trafficking in the primary cilium
- Proteins with proximal-distal asymmetries in axoneme localisation control flagellum beat frequency
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