Hypogonadism and male obesity: Focus on unresolved questions
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Summary
Until longer term, larger RCTs designed for patient‐important outcomes and potential risks are available, testosterone treatment cannot be routinely recommended for men with obesity‐associated nonclassical hypogonadism and lifestyle measures or where indicated bariatric surgery to achieve weight loss, and optimization of comorbidities remain first line.
- Type
- review
- Published
- 2018-07-01
- Cited by
- 131
- References
- 122
- Access
- Open access
- OpenAlex
- https://openalex.org/W2800549049
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:5040467
Keywords
Testosterone (patch), Internal medicine, Medicine, Endocrinology, Obesity
References
- Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest.
- Testosterone Concentrations in Diabetic and Nondiabetic Obese Men
- Male late-onset hypogonadism: pathogenesis, diagnosis and treatment
- The relationship between testosterone and molecular markers of inflammation in older men.
- Trials of testosterone replacement reporting cardiovascular adverse events
- Vigorous Physical Activity is Associated with Regular Aerobic Exercise-Induced Increased Serum Testosterone Levels in Overweight/Obese Men
- Obesity and late-onset hypogonadism.
- The effects of normal aging on the response of the pituitary-gonadal axis to chronic clomiphene administration in men.
- The Progression of Cardiometabolic Disease: Validation of a New Cardiometabolic Disease Staging System Applicable to Obesity
- Comparing effects of low- and high-volume moderate-intensity exercise on sexual function and testosterone in obese men.
- Effects of intermission and resumption of long‐term testosterone replacement therapy on body weight and metabolic parameters in hypogonadal in middle‐aged and elderly men
- Testosterone and obesity
- Obesity-induced hypogonadism in the male: premature reproductive neuroendocrine senescence and contribution of Kiss1-mediated mechanisms.
- The contribution of bone to whole-organism physiology
- Low testosterone levels are common and associated with insulin resistance in men with diabetes.
- Effects of dehydroepiandrosterone and atamestane supplementation on frailty in elderly men.
- Attenuated release of biologically active luteinizing hormone in healthy aging men.
- Expression of functional leptin receptors in rodent Leydig cells.
- Testosterone replacement in older hypogonadal men: a 12-month randomized controlled trial.
- Characteristics of androgen deficiency in late-onset hypogonadism: results from the European Male Aging Study (EMAS).
Cited by
- Diabetes Mellitus: Disorder of Cellular Dysfunction Due to Lack of Entry into Cell of Glucose. The Most Efficient Fuel for Cellular Function*
- Clinical practice update on testosterone therapy for male hypogonadism: Contrasting perspectives to optimize care
- Testosterone-Associated Dietary Pattern Predicts Low Testosterone Levels and Hypogonadism
- Cardiovascular benefits and risks of testosterone replacement therapy in hypogonadal men with type 2 diabetes mellitus and/or the metabolic syndrome: a systematic review
- A body shape index (ABSI) reflects body composition changes in response to testosterone treatment in obese men
- Assessment of Gender-Affirming Hormone Therapy Requirements
- Impact of Metabolically Healthy Obesity in Patients with Andrological Problems.
- Management of Anabolic Steroid-Induced Infertility: Novel Strategies for Fertility Maintenance and Recovery
- An update on heart disease risk associated with testosterone boosting medications
- Reversible male hypogonadotropic hypogonadism due to energy deficit
- Obesity and male hypogonadism: Tales of a vicious cycle
- The association between body mass index and testosterone deficiency in aging Chinese men with benign prostatic hyperplasia: results from a cross-sectional study
- Effects of SHBG rs1799941 Polymorphism on Free Testosterone Levels and Hypogonadism Risk in Young Non-Diabetic Obese Males
- Dietary patterns in relation to testosterone levels and severity of impaired kidney function among middle-aged and elderly men in Taiwan: a cross-sectional study
- Testosterone for Androgen Deficiency-Like Symptoms in Men Without Pathologic Hypogonadism: A Randomized, Placebo-Controlled Cross-Over with Masked Choice Extension Clinical Trial.
- Male Obesity-related Secondary Hypogonadism – Pathophysiology, Clinical Implications and Management
- Vascular Dysfunction among Malaysian Men with Increased BMI: An Indication of Synergistic Effect of Free Testosterone and Inflammation
- Late‐onset hypogonadism: metabolic impact
- Metabolic effects of dopamine agonists in patients with prolactinomas: a systematic review and meta-analysis
- Testicular volume and clinical correlates of hypothalamic–pituitary–testicular function: A cross-sectional study in obese men
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