Constrained Adherable Area of Nanotopographic Surfaces Promotes Cell Migration through the Regulation of Focal Adhesion via Focal Adhesion Kinase/Rac1 Activation.

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Summary

It is suggested that the reduced adherable area promotes cell migration through decreasing the FA formation, which in turn upregulates FAK/Rac1 activation, which is a powerful tool in the research fields involving cell migration such as promoting wound healing and tissue repair.

Type
article
Published
2018-04-12
Cited by
28
References
0
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Open access

Keywords

Focal adhesion, Cell migration, RAC1, Materials science, Extracellular matrix

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