Entering the post-epigenomic age: back to epigenetics
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Summary
In this commentary, the idea of a widespread follow-up use of epigenome editing technology in EWAS studies is propagate to address the questions of which features, where in the genome, and which circumstances are essential to shape development and trigger disease states.
- Type
- article
- Published
- 2018-03-01
- Cited by
- 8
- References
- 69
- Access
- Open access
- OpenAlex
- https://openalex.org/W2795223073
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4589814
Keywords
Epigenome, Epigenomics, Biology, Epigenetics, Epigenesis
References
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- THE EPIGENETIC LANDSCAPE OF ALZHEIMER’S DISEASE
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- Enhancer biology and enhanceropathies
- Locus-specific editing of histone modifications at endogenous enhancers using programmable TALE-LSD1 fusions
- Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome
- A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
- Reprogramming in vivo produces teratomas and iPS cells with totipotency features
- Principles for the post-GWAS functional characterization of cancer risk loci
- Epigenetics and the environment: emerging patterns and implications
- Functional annotation of native enhancers with a Cas9 -histone demethylase fusion
- Epigenetic regulation of vertebrate Hox genes: A dynamic equilibrium
Cited by
- A Customizable Protocol for String Assembly gRNA Cloning (STAgR).
- Chromatin research and biological engineering: an evolving relationship poised for new biomedical impacts
- Systematic Control of Aged Skeletal Muscle Following High-Intensity Stretch-Shortening Contraction Exercise Training: Epigenomic Regulation and Signaling Factors Underpinning Adaptation
- Epigenetic Profiling of Obesity and Smoking
- CRISPR-tools for physiology & cell state changes - potential of transcriptional engineering and epigenome editing.
- Comprehensive histone epigenetics: A mass spectrometry based screening assay to measure epigenetic toxicity
- Stress-induced epigenetic effects driven by maternal lactation in dairy cattle: a comethylation network approach
- A Customizable Protocol for String Assembly gRNA Cloning (STAgR)
- The Pliable Genome: Epigenomics of Norway Spruce
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