Therapeutic implications of the gastrointestinal microbiome.
Explore this paper's citation graph
Summary
The gut microbiome is a rich source of novel therapeutics-pharmabiotics, which can be harnessed to modify host function or alter the gut microbial ecosystem, and these aspects will be highlighted in this review.
- Type
- review
- Published
- 2018-02-01
- Cited by
- 14
- References
- 53
- OpenAlex
- https://openalex.org/W2793187602
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:46799057
Keywords
Microbiome, Gut microbiome, Biology, Function (biology), Human health
References
- Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug
- A possible mechanism of eighteen patient deaths caused by interactions of sorivudine, a new antiviral drug, with oral 5-fluorouracil prodrugs.
- Host-microbial interactions in the metabolism of therapeutic and diet-derived xenobiotics.
- Oral administration of an IL-10-secreting Lactococcus lactis strain prevents food-induced IgE sensitization.
- Bacteriocin production as a mechanism for the antiinfective activity of Lactobacillus salivarius UCC118
- Enteric Microbiome Metabolites Correlate with Response to Simvastatin Treatment
- Efficacy of Prebiotics, Probiotics, and Synbiotics in Irritable Bowel Syndrome and Chronic Idiopathic Constipation: Systematic Review and Meta-analysis
- DNA from probiotic bacteria modulates murine and human epithelial and immune function.
- Diagnosis and Treatment of Clostridium difficile in Adults: A Systematic Review
- Risk and safety of probiotics.
- Reset of a critically disturbed microbial ecosystem: faecal transplant in recurrent Clostridium difficile infection
- Inactivation of digoxin by the gut flora: reversal by antibiotic therapy.
- From yaks to yogurt: the history, development, and current use of probiotics.
- Prodrugs: design and clinical applications
- The gastrointestinal microbiota as a site for the biotransformation of drugs.
- Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism
- Burden of Clostridium difficile Infection in the United States
- Gut microbiota and the role of probiotics in therapy.
- Role of sortase-dependent pili of Bifidobacterium bifidum PRL2010 in modulating bacterium–host interactions
- A phase I trial with transgenic bacteria expressing interleukin-10 in Crohn's disease.
Cited by
- The Lactobacillus Bile Salt Hydrolase Repertoire Reveals Niche-Specific Adaptation
- Let thy food be thy medicine….when possible
- Prebiotics and Probiotics in Digestive Health
- Prebiotics from acorn and sago prevent high-fat diet-induced insulin resistance via microbiome-gut-brain axis modulation
- The Gut Microbiome Influences Responses to Programmed Death 1 Therapy in Chinese Lung Cancer Patients - the Benefits of Diversity.
- Molecular Diagnostic Advances in Transplant Infectious Diseases
- Recent advances in modulating the microbiome
- Evolutionary Study of the Crassphage Virus at Gene Level
- Drug response in association with pharmacogenomics and pharmacomicrobiomics: towards a better personalized medicine
- Effect of Periampullary Diverticulum on Biliary Flora and the Formation of Common Bile Duct Stone
- In vitro digestibility and prebiotic activities of a bioactive polysaccharide from Moringa oleifera leaves.
- Short-chain fatty acid, Butyrate prevents Morphine and Paclitaxel induced peripheral hypersensitivity
- Short-chain fatty acid, butyrate prevents morphine-and paclitaxel-induced nociceptive hypersensitivity
- Effect of Alkaline Mineral Complex Buffer Supplementation on Rumen Fermentation, Rumen Microbiota and Rumen Epithelial Transcriptome of Newborn Calves
Related papers
- Combining metagenomics, metatranscriptomics and viromics to explore novel microbial interactions: towards a systems-level understanding of human microbiome
- Global compositional and functional states of the human gut microbiome in health and disease
- The role of metagenomics in understanding the human microbiome in health and disease
- Application of metagenomics in the human gut microbiome.
- Application of metagenomics in the human gut microbiome
- Metagenomics of the human microbiome
- Metabolic disturbances and the intestinal microbiome
- HumanMycobiomeScan: a new bioinformatics tool for the characterization of the fungal fraction in metagenomic samples