Probing the network structure of health deficits in human aging
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Summary
This work uses computational, information-theoretic, and mean-field approaches to show that the degree distribution and degree correlations of the underlying network are important to the model’s ability to recover the behavior of observational health data.
- Type
- article
- Published
- 2018-02-23
- Cited by
- 24
- References
- 95
- Access
- Open access
- OpenAlex
- https://openalex.org/W2788321129
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:3522103
Keywords
Scale-free network, Network topology, Complex network, Computer science, Observational study
References
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- Scale-Free Networks: A Decade and Beyond
- Evaluation of a frailty index based on a comprehensive geriatric assessment in a population based study of elderly Canadians
- Degree correlation in scale-free graphs
- Ageing: The old worm turns more slowly
- Henry??s Clinical Diagnosis and Management by Laboratory Methods
- Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans
- Assortative mixing in networks.
- Applied Statistics. A Journal of the Royal Statistical Society
Cited by
- Can a Prebiotic Formulation Reduce Frailty Levels in Older People?
- Algorithmic and Stochastic Representations of Gene Regulatory Networks and Protein-Protein Interactions.
- Age-related deficit accumulation and the diseases of ageing.
- Impact of global structure on diffusive exploration of organelle networks
- Proceedings of the Canadian Frailty Network Workshop: Identifying Biomarkers of Frailty to Support Frailty Risk Assessment, Diagnosis and Prognosis. Toronto, January 15, 2018
- Network analysis of frailty and aging: Empirical data from the Mexican Health and Aging Study
- Generating synthetic aging trajectories with a weighted network model using cross-sectional data
- The potential for complex computational models of aging.
- Brain aging and garbage cleaning
- Modelling aging
- Understanding frailty: probabilistic causality between components and their relationship with death through a Bayesian network and evidence propagation
- Measurements of damage and repair of binary health attributes in aging mice and humans reveal that robustness and resilience decrease with age, operate over broad timescales, and are affected differently by interventions
- Network topologies for maximal organismal health span and lifespan.
- Reliability of the Frailty Index Among Community-Dwelling Older Adults
- Modelling lifespan reduction in an exogenous damage model of generic disease
- Short-term Frailty Index Fluctuations in Older Adults: Noise or Signal?
- Demographics of co-ageing complex systems: from infected worms to chess games
- Short-term frailty index fluctuations in older adults: Noise or signal?
- Demographics of co-aging complex systems: from sickly worms to chess engines
- Understanding Frailty: Probabilistic Causality between Components and Their Relationship with Death through a Bayesian Network and Evidence Propagation
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