Smart Cell-Culture Systems: Integration of Sensors and Actuators into Microphysiological Systems
Explore this paper's citation graph
Summary
This review focuses on sensing and actuation schemes that have already been established or offer great potential to provide in situ detection or manipulation of relevant cell or tissue samples in microphysiological platforms and describes two sensor approaches based on surface-plasmon resonance and mechanical resonators that have recently provided new characterization features for biological samples.
- Type
- review
- Published
- 2018-01-30
- Cited by
- 68
- References
- 230
- Access
- Open access
- OpenAlex
- https://openalex.org/W2786679662
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:21733242
Keywords
Computer science, Microfabrication, Multiplexing, Nanotechnology, Throughput
References
- Detection of Micrococcus Luteus Biofilm Formation in Microfluidic Environments by pH Measurement Using an Ion-Sensitive Field-Effect Transistor
- Coincidence detection of heterogeneous cell populations from whole blood with coplanar electrodes in a microfluidic impedance cytometer.
- Microfluidic 3D cell culture: from tools to tissue models.
- Microfluidics: reframing biological enquiry
- Luminescent sensing and imaging of oxygen: Fierce competition to the Clark electrode
- Direct observation of mammalian cell growth and size regulation
- Quartz crystal microbalance with dissipation monitoring: enabling real-time characterization of biological materials and their interactions.
- Real-time, label-free monitoring of cellular invasion and migration with the xCELLigence system
- Lab-on-chip microfluidic system for single cell mass measurement
- Electrochemical Biosensors: Recommended Definitions and Classification
- Label-free cytokine micro- and nano-biosensing towards personalized medicine of systemic inflammatory disorders
- Optomechanical measurement of the stiffness of single adherent cells
- Viability of developmental stages of Schistosoma mansoni quantified with xCELLigence worm real-time motility assay (xWORM)
- A portable cell-based impedance sensor for toxicity testing of drinking water.
- Enzyme SU-8 microreactors: simple tools for cell-culture monitoring
- Metal Oxides and Ion-Exchanging Surfaces as pH Sensors in Liquids: State-of-the-Art and Outlook
- Acoustic Purification of Extracellular Microvesicles
- Polymer-based, flexible glutamate and lactate microsensors for in vivo applications.
- Human Stem Cell-Derived Cardiomyocytes in Cellular Impedance Assays: Bringing Cardiotoxicity Screening to the Front Line
- Real-Time Monitoring of Cell Mechanical Changes Induced by Endothelial Cell Activation and their Subsequent Binding with Leukemic Cell Lines
Cited by
- Remote Cell Growth Sensing Using Self-Sustained Bio-Oscillations
- PDMS-Based Microfluidic Devices for Cell Culture
- Supramolecular Luminescent Sensors.
- Gas Partial Pressure in Cultured Cells: Patho-Physiological Importance and Methodological Approaches
- Microfluidic assay for the on-chip electrochemical measurement of cell monolayer permeability.
- Conjugated Polymers for Assessing and Controlling Biological Functions
- Integrated Microphysiological Systems: Transferable Organ Models and Recirculating Flow
- Monitoring of Microphysiological Systems: Integrating Sensors and Real-Time Data Analysis toward Autonomous Decision-Making
- Microfluidics on the fly: Inexpensive rapid fabrication of thermally laminated microfluidic devices for live imaging and multimodal perturbations of multicellular systems.
- Cell-based biosensors: Recent trends, challenges and future perspectives.
- Isolating Single Euglena gracilis Cells by Glass Microfluidics for Raman Analysis of Paramylon Biogenesis.
- Multi Use Microfluidic Biosensors for Continual Monitoring of Biomarkers from Microphysiological Systems
- Microvascular Mimetics for the Study of Leukocyte–Endothelial Interactions
- Poly-l-Lactic Acid Nanotubes as Soft Piezoelectric Interfaces for Biology: Controlling Cell Attachment via Polymer Crystallinity
- Microphysiological Systems: gold standard approach towards in vitro biomimetics and its potential to drive forward the fisheries sector to the next level
- Integrating Biosensors in Organs-on-Chip Devices: A Perspective on Current Strategies to Monitor Microphysiological Systems
- 3D-Printed electrochemical sensor-integrated transwell systems
- Advances in microfluidic in vitro systems for neurological disease modeling
- Electrochemical Sensing in 3D Cell Culture Models: New Tools for Developing Better Cancer Diagnostics and Treatments
- A microfluidic single-cell array for in situ laminar-flow-based comparative culturing of budding yeast cells.
Related papers
- Transition from one- to two-dimensional development facilitates maintenance of multicellularity
- Bacterial solutions to multicellularity: a tale of biofilms, filaments and fruiting bodies
- Progress of Two-Photon Three-Dimensional Microfabrication
- Status and principle of two-photon microfabrication using femtosecond laser
- Building a multicellular organism.
- Varied solutions to multicellularity: The biophysical and evolutionary consequences of diverse intercellular bonds
- The Evolution of Multicellularity: A Minor Major Transition?
- Throughput-based switching between diversity and multiplexing in MIMO systems
- Combined switching and power control for diversity and multiplexing in MIMO systems with cochannel interference