Long noncoding RNAs: Undeciphered cellular codes encrypting keys of colorectal cancer pathogenesis
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Summary
This review will focus on key lncRNAs with the high potential as CRC-specific biomarkers in this review of numerous notable lnc RNAs identified and characterized in CRC.
- Type
- review
- Published
- 2018-01-03
- Cited by
- 54
- References
- 83
- Access
- Open access
- OpenAlex
- https://openalex.org/W2782238352
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:3539595
Keywords
Biology, Computational biology, Long non-coding RNA, Colorectal cancer, RNA
References
- Highly expressed long non‐coding RNA CRNDE promotes cell proliferation through PI3K/AKT signalling in non‐small cell lung carcinoma
- RNA Editing in Pathogenesis of Cancer.
- Enhanced expression of long noncoding RNA CARLo-5 is associated with the development of gastric cancer.
- RNA editing of non-coding RNA and its role in gene regulation.
- The Novel Gene CRNDE Encodes a Nuclear Peptide (CRNDEP) Which Is Overexpressed in Highly Proliferating Tissues
- MYC regulates the non-coding transcriptome
- MicroRNAs in cancer: personalizing diagnosis and therapy
- MYC-repressed long noncoding RNAs antagonize MYC-induced cell proliferation and cell cycle progression
- Long non-coding RNA CCAL regulates colorectal cancer progression by activating Wnt/β-catenin signalling pathway via suppression of activator protein 2α
- The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling
- MicroRNAs and leukemias: how strong is the connection?
- DNA variations in human and medical genetics: 25 years of my experience
- Long non-coding RNA CARLo-5 is a negative prognostic factor and exhibits tumor pro-oncogenic activity in non-small cell lung cancer
- CRNDE, a long non-coding RNA responsive to insulin/IGF signaling, regulates genes involved in central metabolism.
- A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21
- 'Lnc'-ing enhancers to MYC regulation
- Functions of noncoding sequences in mammalian genomes
- Genome-wide analysis of non-coding regulatory mutations in cancer
- Association between polymorphisms in long non-coding RNA PRNCR1 in 8q24 and risk of colorectal cancer
- CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer
Cited by
- LncRNA NEAT1 promotes colorectal cancer cell proliferation and migration via regulating glial cell-derived neurotrophic factor by sponging miR-196a-5p
- The novel long noncoding RNA u50535 promotes colorectal cancer growth and metastasis by regulating CCL20
- LncRNA CRNDE is a biomarker for clinical progression and poor prognosis in clear cell renal cell carcinoma
- Single nucleotide polymorphisms and sporadic colorectal cancer susceptibility: a field synopsis and meta-analysis
- Epigenetic Regulation by lncRNAs: An Overview Focused on UCA1 in Colorectal Cancer
- Long noncoding RNA HAGLROS regulates apoptosis and autophagy in colorectal cancer cells via sponging miR‐100 to target ATG5 expression
- MNX1-AS1 is a functional oncogene that induces EMT and activates the AKT/mTOR pathway and MNX1 in breast cancer
- Long noncoding RNA SNHG6 functions as a competing endogenous RNA by sponging miR-181a-5p to regulate E2F5 expression in colorectal cancer
- A novel lncRNA NR4A1AS upregulates orphan nuclear receptor NR4A1 expression by blocking UPF1-mediated mRNA destabilization in colorectal cancer.
- The Intricate Interplay between Epigenetic Events, Alternative Splicing and Noncoding RNA Deregulation in Colorectal Cancer
- The identification of CRNDE, H19, UCA1 and HOTAIR as the key lncRNAs involved in oxaliplatin or irinotecan resistance in the chemotherapy of colorectal cancer based on integrative bioinformatics analysis
- Long Non-Coding RNA in the Pathogenesis of Cancers
- Insulin-Like Growth Factor 2 (IGF2) Signaling in Colorectal Cancer—From Basic Research to Potential Clinical Applications
- MiR-6803-5p Promotes Cancer Cell Proliferation and Invasion via PTPRO/NF-κB Axis in Colorectal Cancer
- TEAD4 modulated LncRNA MNX1-AS1 contributes to gastric cancer progression partly through suppressing BTG2 and activating BCL2
- LncRNA, a novel target biomolecule, is involved in the progression of colorectal cancer.
- LncRNA profile study reveals a seven-lncRNA signature predicts the prognosis of patients with colorectal cancer
- Long Noncoding RNAs Control the Modulation of Immune Checkpoint Molecules in Cancer
- Knockdown of ZEB2-AS1 inhibits cell invasion and induces apoptosis in colorectal cancer.
- The Downregulation of lncRNA pgm5-as1 Inhibits the Proliferation and Metastasis Via Increasing miR-484 Expression in Colorectal Cancer
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