Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma: A Randomized Clinical Trial
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Summary
In the final analysis of this randomized clinical trial of patients with glioblastoma who had received standard radiochemotherapy, the addition of TTFields to maintenance temozolomide chemotherapy vs maintenance Temozolmide alone, resulted in statistically significant improvement in progression-free survival and overall survival.
- Type
- article
- Published
- 2017-12-19
- Cited by
- 2,259
- References
- 53
- Access
- Open access
- OpenAlex
- https://openalex.org/W2778283729
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25211086
Keywords
Temozolomide, Medicine, Glioblastoma, Oncology, Internal medicine
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Cited by
- Dosimetric impact of tumor treating field (TTField) transducer arrays onto treatment plans for glioblastomas – a planning study
- Applications of human brain organoids to clinical problems
- Tumor Treating Fields for Ovarian Carcinoma: A Modeling Study
- CGCG clinical practice guidelines for the management of adult diffuse gliomas.
- Radiosurgery for Glioblastoma.
- CNS cancer: TTFields improve survival
- Tumor treating fields: a new approach to glioblastoma therapy
- IDO1 inhibition synergizes with radiation and PD-1 blockade to durably increase survival against advanced glioblastoma
- New Directions in the Treatment of Glioblastoma
- Use of FET PET in glioblastoma patients undergoing neurooncological treatment including tumour-treating fields: initial experience
- Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial
- Malignancy Index Using Intraoperative Flow Cytometry is a Valuable Prognostic Factor for Glioblastoma Treated With Radiotherapy and Concomitant Temozolomide
- Current state of immunotherapy for glioblastoma
- Molecular Targeting of Acid Ceramidase in Glioblastoma: A Review of Its Role, Potential Treatment, and Challenges
- Quality of Life in Patients With Glioblastoma Treated With Tumor-Treating Fields.
- The National Resident Matching Program and Competition for Employment.
- BRAF inhibition with concomitant tumor treating fields for a multiply progressive pleomorphic xanthoastrocytoma
- Tumor-treating fields as a fourth treating modality for glioblastoma: a meta-analysis
- The Effect of Pet Therapy and Artist Interactions on Quality of Life in Brain Tumor Patients: A Cross-Section of Art and Medicine in Dialog
- Kaum überzeugend: Schwerionen und Methadon bei Hirntumoren
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