Antioxidants Maintain Cellular Redox Homeostasis by Elimination of Reactive Oxygen Species
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Summary
The roles of cellular endogenous antioxidant systems as well as natural anti-oxidative compounds in several human diseases caused by ROS are summarized in order to illustrate the vital role of antioxidants in prevention against oxidative stress.
- Type
- review
- Published
- 2017-11-17
- Cited by
- 1,856
- References
- 187
- Access
- Open access
- OpenAlex
- https://openalex.org/W2769622412
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:5076378
Keywords
Reactive oxygen species, Oxidative stress, Cell biology, Superoxide dismutase, Thioredoxin
References
- Mitochondrial ROS in cancer: initiators, amplifiers or an Achilles’ heel?
- Role of Hyperketonemia in Inducing Oxidative Stress and Cellular Damage in Cultured Hepatocytes and Type 1 Diabetic Rat Liver
- Licochalcone A-induced human gastric cancer BGC-823 cells apoptosis by regulating ROS-mediated MAPKs and PI3K/AKT signaling pathways
- Regulation of gene expression by CAR: an update
- Reactive Oxygen and Nitrogen Species in Steatotic Hepatocytes: A Molecular Perspective on the Pathophysiology of Ischemia-Reperfusion Injury in the Fatty Liver
- Glutathione peroxidase family – an evolutionary overview
- Preparation and assay of mammalian thioredoxin and thioredoxin reductase.
- Pregnane X Receptor as the “Sensor and Effector” in Regulating Epigenome
- Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
- Host lysozyme-mediated lysis of Lactococcus lactis facilitates delivery of colitis-attenuating superoxide dismutase to inflamed colons
- Thioredoxin and glutaredoxin systems.
- Flavoprotein disulfide reductases: advances in chemistry and function.
- Puerarin Protects Human Neuroblastoma SH‐SY5Y Cells against Glutamate‐Induced Oxidative Stress and Mitochondrial Dysfunction
- Sulforaphane exerts its anti-inflammatory effect against amyloid-β peptide via STAT-1 dephosphorylation and activation of Nrf2/HO-1 cascade in human THP-1 macrophages.
- Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals.
- Uric Acid as a CNS Antioxidant
- Ethanol‐induced cytochrome P4502E1 causes carcinogenic etheno‐DNA lesions in alcoholic liver disease
- Redox signaling and the MAP kinase pathways
- Antioxidant properties of 4-vinyl derivatives of hydroxycinnamic acids.
- Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
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- Mechanistic insight into the in vitro toxicity of graphene oxide against biofilm forming bacteria using laser-induced breakdown spectroscopy.
- Implications of PI3K/AKT/PTEN Signaling on Superoxide Dismutases Expression and in the Pathogenesis of Alzheimer’s Disease
- Chelerythrine induced cell death through ROS-dependent ER stress in human prostate cancer cells
- Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry.
- Antioxidant Enzymes and Lipid Peroxidation in Alloxan-Induced Diabetic Rabbits
- Anti-Proliferative and Apoptotic Effects of Polygonum cuspidatum and its Bioactive Compound, Emodin, in Colorectal Carcinoma HT-29 cells
- Chelating and antioxidant properties of l-Dopa containing tetrapeptide for the treatment of neurodegenerative diseases.
- Bacterial inactivation and in situ monitoring of biofilm development on graphene oxide membrane using optical coherence tomography
- Consequences on aging process and human wellness of generation of nitrogen and oxygen species during strenuous exercise
- Effect of P450 Oxidoreductase Polymorphisms on the Metabolic Activities of Ten Cytochrome P450s Varied by Polymorphic CYP Genotypes in Human Liver Microsomes
- Autophagy: The Last Defense against Cellular Nutritional Stress.
- Modulation of the Oxidative Stress and Lipid Peroxidation by Endocannabinoids and Their Lipid Analogues
- Lactate dehydrogenases amplify reactive oxygen species in cancer cells in response to oxidative stimuli
- Low concentrations of clarithromycin upregulate cellular antioxidant enzymes and phosphorylation of extracellular signal-regulated kinase in human small airway epithelial cells
- Inhibition of Neointima Hyperplasia, Inflammation, and Reactive Oxygen Species in Balloon-Injured Arteries by HVJ Envelope Vector-Mediated Delivery of Superoxide Dismutase Gene
- Molecular Mechanisms Involved in Oxidative Stress-Associated Liver Injury Induced by Chinese Herbal Medicine: An Experimental Evidence-Based Literature Review and Network Pharmacology Study
- Antioxidative CXXC Peptide Motif From Mesencephalic Astrocyte-Derived Neurotrophic Factor Antagonizes Programmed Cell Death
- Effect of matrix metalloproteinase 8 inhibitor and chlorhexidine on the cytotoxicity, oxidative stress and cytokine level of MDPC-23.
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