Multiplexed Temporal Quantification of the Exercise-regulated Plasma Peptidome*
Explore this paper's citation graph
Summary
Deep peptidomic analysis of plasma revealed that exercise rapidly modulates the circulation of hundreds of bioactive peptides through a network of proteases and PTMs, illustrating that peptidomics is an ideal method for quantifying changes in circulating factors on a global scale in response to physiological perturbations such as exercise.
- Type
- article
- Published
- 2017-10-05
- Cited by
- 59
- References
- 54
- Access
- Open access
- OpenAlex
- https://openalex.org/W2762735072
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:36541415
Keywords
Computational biology, Chemistry, Biology
References
- BIOPEP database and other programs for processing bioactive peptide sequences.
- Magnetic Bead-Based Serum Peptidome Profiling in Patients with Gestational Diabetes Mellitus
- Glucagon and plasma catecholamine responses to graded and prolonged exercise in man.
- SATPdb: a database of structurally annotated therapeutic peptides
- Effectiveness of CID, HCD, and ETD with FT MS/MS for degradomic-peptidomic analysis: comparison of peptide identification methods
- Soluble plasma HLA peptidome as a potential source for cancer biomarkers
- Endorphins: "opiates for the masses".
- Strenuous exercise promotes shear-induced thrombin generation by increasing the shedding of procoagulant microparticles from platelets
- Peptidomics: the integrated approach of MS, hyphenated techniques and bioinformatics for neuropeptide analysis.
- Transgelins, cytoskeletal proteins implicated in different aspects of cancer development
- Urinary Proteomic Biomarkers in Coronary Artery Disease*S
- Integrative biology of exercise.
- Analysis of the plasma peptidome from pancreas cancer patients connects a peptide in plasma to overexpression of the parent protein in tumors.
- Expanding the detectable HLA peptide repertoire using electron-transfer/higher-energy collision dissociation (EThcD)
- Assessing the effects of diurnal variation on the composition of human parotid saliva: quantitative analysis of native peptides using iTRAQ reagents.
- Analysis of SM22α-Deficient Mice Reveals Unanticipated Insights into Smooth Muscle Cell Differentiation and Function
- Selective enrichment of sialic acid–containing glycopeptides using titanium dioxide chromatography with analysis by HILIC and mass spectrometry
- A label-free nano-liquid chromatography-mass spectrometry approach for quantitative serum peptidomics in Crohn's disease patients.
- Endorphins: what are they? How are they measured? What is their role in exercise?
- Mechanism of C-terminal amide formation by pituitary enzymes
Cited by
- Changes to the Human Serum Proteome in Response to High Intensity Interval Exercise: A Sequential Top-Down Proteomic Analysis
- Comparison of Urine and Plasma Peptidome Indicates Selectivity in Renal Peptide Handling
- Exercise, Obesity and CNS Control of Metabolic Homeostasis: A Review
- Peptidomic analysis of endogenous plasma peptides from patients with pancreatic neuroendocrine tumours
- Salicylic acid influences the protease activity and posttranslation modifications of the secreted peptides in the moss Physcomitrella patens
- Phytohormone treatment induces generation of cryptic peptides with antimicrobial activity in the Moss Physcomitrella patens
- The Plethora of Angiotensin-Converting Enzyme-Processed Peptides in Mouse Plasma
- Current advances in our understanding of exercise as medicine in metabolic disease
- Small-protein Enrichment Assay Enables the Rapid, Unbiased Analysis of Over 100 Low Abundance Factors from Human Plasma*
- Novel mechanisms and biomarkers in alcohol-induced organ injury.
- Mass Spectrometry-Based Plasma Proteomics: Considerations from Sample Collection to Achieving Translational Data
- Diurnal variation of inflammatory plasma proteins involved in pain
- Loss of O-linked protein glycosylation in Burkholderia cenocepacia impairs biofilm formation and siderophore production via alteration of quorum sensing regulation
- Biobanking for discovery of novel cardiovascular biomarkers using imaging-quantified disease burden: protocol for the longitudinal, prospective, BioHEART-CT cohort study
- The Emerging Roles of Nicotinamide Adenine Dinucleotide Phosphate Oxidase 2 in Skeletal Muscle Redox Signaling and Metabolism
- Loss of O-Linked Protein Glycosylation in Burkholderia cenocepacia Impairs Biofilm Formation and Siderophore Activity and Alters Transcriptional Regulators
- Advancing serum peptidomic profiling by data-independent acquisition for clear-cell renal cell carcinoma detection and biomarker discovery.
- Peptidomic analyses: The progress in enrichment and identification of endogenous peptides
- Label-free peptide quantification coupled with in silico mapping of proteases for identification of potential serum biomarkers in gastric adenocarcinoma patients.
- Mass spectrometric characterisation of the circulating peptidome following oral glucose ingestion in control and gastrectomised patients
Related papers
- ФОРМИРОВAНИЕ ГОТОВНОСТИ БУДУЩИХ ПЕДAГОГОВ К ОРГAНИЗAЦИИ РAБОТЫ ПО РAЗВИТИЮ ВAЛЕОЛОГИЧЕСКОЙ КУЛЬТУРЫ ШКОЛЬНИКОВ
- DETERMINING QUALITY REQUIREMENTS AT THE UNIVERSITIES TO IMPROVE THE QUALITY OF EDUCATION
- A GEOMETRIC MEAN IN THE FURUTA INEQUALITY
- ИСПОЛЬЗОВAНИЕ ПОТЕНЦИAЛA СОЦИAЛЬНЫХ ПAРТНЕРОВ В ПОДГОТОВКЕ БУДУЩИХ ПЕДAГОГОВ
- Darstellung perhalogenierter Dimethyldisulfane durch photochemische Reaktion von CSF2 und CSFCI mit Sulfenylbromiden bzw. ‐chloriden
- Chemistry of geminal diazides. Rearrangements to N-Cyano compounds