Salt-inducible kinases in adipose tissue
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Summary
The data suggest that insulin resistance might be a causal factor underlying the downregulation of SIK2 in human adipose tissue, and might provide an attractive therapeutic target for the treatment of metabolic diseases in the future.
- Published
- 2017-01-01
- Cited by
- 0
- References
- 164
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:31440762
References
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- The Genotype-Tissue Expression (GTEx) project
- Cloning of a novel kinase (SIK) of the SNF1/AMPK family from high salt diet‐treated rat adrenal1
- Identification of AMPK phosphorylation sites reveals a network of proteins involved in cell invasion and facilitates large-scale substrate prediction
- Salt‐inducible kinase 3 deficiency exacerbates lipopolysaccharide‐induced endotoxin shock accompanied by increased levels of pro‐inflammatory molecules in mice
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