The long non-coding RNA Neat1 is an important mediator of the therapeutic effect of bexarotene on traumatic brain injury in mice.
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Summary
The in vitro anti-apoptotic and anti-inflammatory effects of Neat1 were further confirmed in C57BL/6 mice, which resulted in better functional recovery in mice after TBI.
- Type
- article
- Published
- 2017-10-01
- Cited by
- 94
- References
- 54
- OpenAlex
- https://openalex.org/W2611587147
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4762805
Keywords
Gene knockdown, Neuroprotection, Bexarotene, Traumatic brain injury, Apoptosis
References
- Altered Long Noncoding RNA Expression Precedes the Course of Parkinson’s Disease—a Preliminary Report
- Pidd, a new death-domain–containing protein, is induced by p53 and promotes apoptosis
- Bexarotene-Activated Retinoid X Receptors Regulate Neuronal Differentiation and Dendritic Complexity
- Role of HO-1 in the Arsenite-Induced Neurotoxicity in Primary Cultured Cortical Neurons
- Long noncoding RNAs: Cellular address codes in development and disease
- Activation of RXR–PPAR heterodimers by organotin environmental endocrine disruptors
- Inhibitor of Differentiation-1 and Hypoxia-Inducible Factor-1 Mediate Sonic Hedgehog Induction by Amyloid Beta-Peptide in Rat Cortical Neurons
- Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease
- Retinoic acid in the development, regeneration and maintenance of the nervous system
- Oncofetal long noncoding RNA PVT1 promotes proliferation and stem cell‐like property of hepatocellular carcinoma cells by stabilizing NOP2
- Integrating the roles of long and small non-coding RNA in brain function and disease
- Integration of genome-wide approaches identifies lncRNAs of adult neural stem cells and their progeny in vivo
- Noncoding RNAs: key molecules in understanding and treating pain
- Long noncoding RNA NEAT1-dependent SFPQ relocation from promoter region to paraspeckle mediates IL8 expression upon immune stimuli.
- Somatosensory evoked potentials as predictors of outcome in patients with acute diffuse axonal injury.
- DNA damage- and stress-induced apoptosis occurs independently of PIDD
- Computational approaches towards understanding human long non-coding RNA biology
- Nuclear initiated NF-κB signaling: NEMO and ATM take center stage
- 1,3-Bis(2-chloroethyl)-1-nitrosourea enhances the inhibitory effect of resveratrol on 5-fluorouracil sensitive/resistant colon cancer cells.
- The fate of dsRNA in the nucleus: a p54(nrb)-containing complex mediates the nuclear retention of promiscuously A-to-I edited RNAs.
Cited by
- Steroid and Xenobiotic Receptor Signalling in Apoptosis and Autophagy of the Nervous System
- Circular RNA Expression Profiles Alter Significantly after Traumatic Brain Injury in Rats
- Bexarotene protects against neurotoxicity partially through a PPARγ-dependent mechanism in mice following traumatic brain injury.
- Autophagy in Traumatic Brain Injury: A New Target for Therapeutic Intervention
- Evolution of cerebral perfusion in the peri-contusional cortex in mice revealed by in vivo laser speckle imaging after traumatic brain injury.
- Clinical and Basic Evaluation of the Prognostic Value of Uric Acid in Traumatic Brain Injury
- Protective effects of lncRNA H19 silence against hypoxia-induced injury in PC-12 cells by regulating miR-28.
- Prenatal Exposure to Benzophenone-3 Impairs Autophagy, Disrupts RXRs/PPARγ Signaling, and Alters Epigenetic and Post-Translational Statuses in Brain Neurons
- NEAT1 and paraspeckles in neurodegenerative diseases: A missing lnc found?
- Significant changes in circular RNA in the mouse cerebral cortex around an injury site after traumatic brain injury
- Non-Coding RNAs to Aid in Neurological Prognosis after Cardiac Arrest
- Rapamycin improves the neuroprotection effect of inhibition of NLRP3 inflammasome activation after TBI.
- The Implications of the Long Non-Coding RNA NEAT1 in Non-Cancerous Diseases
- Long noncoding RNA nuclear enriched abundant transcript 1 promotes the proliferation and migration of Schwann cells by regulating the miR‐34a/Satb1 axis
- Bexarotene Exerts Protective Effects Through Modulation of the Cerebral Vascular Smooth Muscle Cell Phenotypic Transformation by Regulating PPARγ/FLAP/LTB4 After Subarachnoid Hemorrhage in Rats
- NEAT1 involves Alzheimer’s Disease (AD) progression via regulation of glycolysis and P-tau
- The role of long noncoding RNA in traumatic brain injury
- Long noncoding RNA Neat1 modulates myogenesis by recruiting Ezh2
- YY1-induced upregulation of lncRNA NEAT1 contributes to OGD/R injury-induced inflammatory response in cerebral microglial cells via Wnt/β-catenin signaling pathway
- Long Non-coding RNA in CNS Injuries: A New Target for Therapeutic Intervention
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