In Vivo Enzymes Activities of Some Ru(II) Compounds with N-Alkylphenothiazines
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Summary
Results of the present study suggest the neuro- and cardio protective potential of oral administration of ruthenium complexes 1 and 2, as non-toxic compounds under physiological conditions, are the result of their potent antioxidant activity.
- Type
- article
- Published
- 2016-12-01
- Cited by
- 0
- References
- 47
- Access
- Open access
- OpenAlex
- https://openalex.org/W2575733397
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:41179420
Keywords
Lactate dehydrogenase, In vivo, Trifluoperazine, Enzyme, Chemistry
References
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- Synthesis, characterization, and spectral studies of lanthanide(III) nitrate complexes of promethazine
- A new and rapid colorimetric determination of acetylcholinesterase activity.
- New ruthenium(II) complexes with N-alkylphenothiazines: synthesis, structure, in vivo activity as free radical scavengers and in vitro cytotoxicity.
- Complexes of hydroxamates III.: Equilibrium and kinetic studies on the reactions of iron(III) with monohydroxamic acids
- Synthesis, structural and spectroscopic characterization, in vitro cytotoxicity and in vivo activity as free radical scavengers of chlorido(p-cymene) complexes of ruthenium(II) containing N-alkylphenothiazines.
- Lactate Dehydrogenase Isoenzymes 1 and 5: Differential Expression by Neoplastic and Stromal Cells in Non-Small Cell Lung Cancer and Other Epithelial Malignant Tumors
- Synthesis and reactivity of organolanthanide complexes containing phenothiazine ligand toward carbodiimide and isothiocyanate
- Metal Cu(II) and Zn(II) bipyridyls as inhibitors of lactate dehydrogenase
- Acetylcholinesterase: enzyme structure, reaction dynamics, and virtual transition states
- RutheniumII(η6-arene) Complexes of Thiourea Derivatives: Synthesis, Characterization and Urease Inhibition
- Synthesis and anticancer activity of ruthenium half-sandwich complexes comprising combined metal centrochirality and planar chirality
- Synthesis and characterisation of some water soluble ruthenium(II)–arene complexes and an investigation of their antibiotic and antiviral properties
- Effect of ruthenium complexes on the activities of succinate dehydrogenase and cytochrome oxidase.
- Ruthenium(II) complexes with hydroxypyridinecarboxylates: Screening potential metallodrugs against Mycobacterium tuberculosis
- Preclinical combination therapy of the investigational drug NAMI-A+ with doxorubicin for mammary cancer
- Changes in readthrough acetylcholinesterase expression modulate amyloid-beta pathology.
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