Roles of Caspases in Necrotic Cell Death
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Summary
Recent advances have significantly expanded the understanding of the roles of caspases in regulating development, adult homeostasis and host defense response.
- Type
- review
- Published
- 2016-12-15
- Cited by
- 260
- References
- 100
- Access
- Open access
- OpenAlex
- https://openalex.org/W2566836667
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:206562489
Keywords
Biology, Caspase, Programmed cell death, Apoptosis, Cell biology
References
- Characterization of a functional NF-kappa B site in the human interleukin 1 beta promoter: evidence for a positive autoregulatory loop
- Necroptosis in health and diseases.
- Apoptotic Pathways: The Roads to Ruin
- NEMO/IKKγ regulates an early NF-κB-independent cell death checkpoint during TNF signaling
- Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule
- The ubiquitin-modifying enzyme A20 restricts the ubiquitination of RIPK3 and protects cells from necroptosis
- Differential susceptibility to lethal endotoxaemia in mice deficient in IL‐1α, IL‐1β or IL‐1 receptor type I
- IAPs limit activation of RIP kinases by TNF receptor 1 during development
- Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
- Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
- The Prevalence of TNFα-Induced Necrosis over Apoptosis Is Determined by TAK1-RIP1 Interplay
- Catalytic activity of the caspase-8-FLIPL complex inhibits RIPK3-dependent necrosis
- Phosphorylation-Driven Assembly of RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
- Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases
- Guanylate binding proteins promote caspase-11–dependent pyroptosis in response to cytoplasmic LPS
- Molecular cloning of the interleukin-1 beta converting enzyme.
- Caspase‐1‐dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages
- Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis.
- The function of TRADD in signaling via tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors
- In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains.
Cited by
- Caspase-11-mediated tubular epithelial pyroptosis underlies contrast-induced acute kidney injury
- The ATM kinase inhibitor KU-55933 provides neuroprotection against hydrogen peroxide-induced cell damage via a γH2AX/p-p53/caspase-3-independent mechanism: Inhibition of calpain and cathepsin D.
- The Contribution of Necroptosis in Neurodegenerative Diseases
- TNF superfamily receptor OX40 triggers invariant NKT cell pyroptosis and liver injury
- Caspases and their substrates
- Proteases Revisited: Roles and Therapeutic Implications in Fibrosis
- Role of apoptosis in the development of autosomal dominant polycystic kidney disease (ADPKD)
- Investigation of the expression of apoptosis-inducing factor-mediated apoptosis in Hirschsprung’s disease
- Proteolytic control of regulated necrosis.
- The neurotoxicant PCB‐95 by increasing the neuronal transcriptional repressor REST down‐regulates caspase‐8 and increases Ripk1, Ripk3 and MLKL expression determining necroptotic neuronal death
- Apoptosis inhibitor of macrophage ameliorates fungus-induced peritoneal injury model in mice
- Chromosome 17q21 Genes ORMDL3 and GSDMB in Asthma and Immune Diseases.
- Oncogenic RAS-induced downregulation of ATG12 is required for survival of malignant intestinal epithelial cells
- Caspase-11–mediated endothelial pyroptosis underlies endotoxemia-induced lung injury
- Hepatic neuregulin 4 signaling defines an endocrine checkpoint for steatosis-to-NASH progression
- In vivo and in vitro induction of the apoptotic effects of oxysophoridine on colorectal cancer cells via the Bcl-2/Bax/caspase-3 signaling pathway
- Epidermal cornification is preceded by the expression of a keratinocyte-specific set of pyroptosis-related genes
- Synthesis and anti-tumor activity of EF24 analogues as IKKβ inhibitors.
- Loss of A20 in BM-MSCs regulates the Th17/Treg balance in Rheumatoid Arthritis
- Role of p62 in the regulation of cell death induction
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