The Relationships Between Regional Arterial Inflammation, Calcification, Risk Factors and Biomarkers – A Prospective FDG PET/CT Imaging Study
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Summary
FDG PET imaging can increase knowledge of how atherosclerotic plaque inflammation relates to calcification, serum biomarkers, and vascular risk factors, and the atheroprotective biomarker adiponectin was negatively correlated with the degree of arterial inflammation in the descending aorta.
- Type
- article
- Published
- 2009-01-26
- Cited by
- 253
- References
- 34
- Access
- Open access
- OpenAlex
- https://openalex.org/W2549058675
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:9491192
Keywords
Medicine, Inflammation, Cardiology, Internal medicine, Biomarker
References
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- (18)Fluorodeoxyglucose positron emission tomography imaging of atherosclerotic plaque inflammation is highly reproducible: implications for atherosclerosis therapy trials.
- MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial.
- Simvastatin attenuates plaque inflammation: evaluation by fluorodeoxyglucose positron emission tomography.
- (18)F-FDG accumulation in atherosclerotic plaques: immunohistochemical and PET imaging study.
- Association of vascular 18F-FDG uptake with vascular calcification.
- Characterization of plaques using 18F-FDG PET/CT in patients with carotid atherosclerosis and correlation with matrix metalloproteinase-1.
- Adiponectin inversely correlates with high sensitive C-reactive protein and triglycerides, but not with insulin sensitivity, in apparently healthy Japanese men.
- Clinical Usefulness of Very High and Very Low Levels of C-Reactive Protein Across the Full Range of Framingham Risk Scores
- Vascular inflammation evaluated by [18F]-fluorodeoxyglucose positron emission tomography is associated with the metabolic syndrome.
- Form to function: current and future roles for atherosclerosis imaging in drug development
- Increased matrix metalloproteinase-9 activity in unstable carotid plaques. A potential role in acute plaque disruption.
- Serpins, the vasculature, and viral therapeutics.
- The prevalence of inflammation in carotid atherosclerosis: analysis with fluorodeoxyglucose-positron emission tomography.
- Do high glucose levels have differential effect on FDG uptake in inflammatory and malignant disorders?
- From 2D PET to 3D PET: issues of data representation and image reconstruction.
- Noninvasive in vivo measurement of vascular inflammation with F-18 fluorodeoxyglucose positron emission tomography
- Adiponectin as an anti-inflammatory factor.
- Macrophage expression of active MMP-9 induces acute plaque disruption in apoE-deficient mice.
- Atherosclerosis Inflammation Imaging with 18F-FDG PET: Carotid, Iliac, and Femoral Uptake Reproducibility, Quantification Methods, and Recommendations
Cited by
- Association of atherosclerosis in the descending thoracic aorta with coronary artery disease on multi detector row computed tomography coronary angiography in patients with suspected coronary artery disease
- Coronary arterial 18F-sodium fluoride uptake: a novel marker of plaque biology.
- Imaging of the aortic valve using fluorodeoxyglucose positron emission tomography increased valvular fluorodeoxyglucose uptake in aortic stenosis.
- Pelvis: normal variants and benign findings in FDG-PET/CT imaging.
- Annexin A1 and annexin A5 in cardiovascular disease
- Noninvasive vascular ultrasound elastography
- Influence of thoracic aortic inflammation and calcifications on arterial stiffness and cardiac function in older subjects
- Prevalence and Risk Factors of Carotid Vessel Wall Inflammation in Coronary Artery Disease Patients
- Comparison of 64Cu and 68Ga for Molecular Imaging of Atherosclerosisusing the Apolipoprotein A-I Mimetic Peptide FAMP
- Imaging atherosclerotic plaque inflammation by fluorodeoxyglucose with positron emission tomography: ready for prime time?
- Serum Inflammatory Biomarkers and Plaque Inflammation Assessed by 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the dal-PLAQUE Study
- Vascular imaging with positron emission tomography
- Aortic 18F-FDG uptake in patients suffering from granulomatosis with polyangiitis
- Correlation of biomechanics to tissue reaction in aortic aneurysms assessed by finite elements and [18F]–fluorodeoxyglucose–PET/CT
- Validity of Vascular Calcification as a Screening Tool and as a Surrogate End Point in Clinical Research.
- F-18-FDG Imaging for Atherosclerotic Plaque Characterization
- Carotid plaque inflammation on 18F‐fluorodeoxyglucose positron emission tomography predicts early stroke recurrence
- FDG PET Imaging and Cardiovascular Inflammation
- Large-Vessel Vasculitis: Interobserver Agreement and Diagnostic Accuracy of 18F-FDG-PET/CT
- Capping it off
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