Precision medicine: from pharmacogenomics to pharmacoproteomics
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Summary
The current status of pharmacogenomics in precision medicine is discussed and the needs for concordant analysis at the proteome and metabolome levels via the more recently-evolved fields of pharmacoproteomics, toxicoproteinomics, and pharmacometabolomics are highlighted.
- Type
- review
- Published
- 2016-09-26
- Cited by
- 48
- References
- 87
- Access
- Open access
- OpenAlex
- https://openalex.org/W2526474391
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:15823923
Keywords
Pharmacogenomics, Precision medicine, Proteome, Omics, Drug development
References
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Cited by
- Development of Targeted Therapies Based on Gene Modification.
- Identifying Common Therapeutic Targets in Merlin-deficient Brain Tumours
- Environmental influences in the etiology of colorectal cancer: the premise of metabolomics
- Clinical application of a microfluidic chip for immunocapture and quantification of circulating exosomes to assist breast cancer diagnosis and molecular classification
- Historical root of precision medicine: an ancient concept concordant with the modern pharmacotherapy
- Pulmonary arterial hypertension – progress in understanding the disease and prioritizing strategies for drug development
- Clinical multi-omics strategies for the effective cancer management.
- DrugBank 5.0: a major update to the DrugBank database for 2018
- Toward novel therapeutics for functional constipation :from traditional Chinese medicine herbal formula MaZiRenWan to cyclic spexin analogues
- Biomarkers: Delivering on the expectation of molecularly driven, quantitative health
- Integrating community driven care service in European welfare states nonprofit institutional entrepreneurship as driver for expanding access
- Onco-proteogenomic exploration of variant peptide detection in disease models and clinical specimens
- Discovery of the Consistently Well-Performed Analysis Chain for SWATH-MS Based Pharmacoproteomic Quantification
- Additive manufacturing of pharmaceuticals for precision medicine applications: A review of the promises and perils in implementation
- Clinical Pharmacogenetics for Precision Medicine: Successes and Setbacks.
- High-Resolution Melting Assay for Genotyping Variants of the CYP2C19 Enzyme and Predicting Voriconazole Effectiveness
- Biotransformation profiles from a cohort of chronic fatigue women in response to a hepatic detoxification challenge
- A Novel Patient-specific Protein Expression-based Algorithmic Model for Immune Checkpoint Inhibition Therapy Response Prediction in a Pan-cancer Cohort
- An integrative resource for investigating genetic model of drug response in cancer
- Pharmaco-Geno-Proteo-Metabolomics and Translational Research in Cancer.
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