Making Sense of the Tangle: Insights into Chromatin Folding and Gene Regulation
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Summary
Deciphering the chromatin tangle requires comprehensive integrative analyses of DNA- and protein-dependent factors that regulate genomic organization.
- Type
- review
- Published
- 2016-09-23
- Cited by
- 14
- References
- 76
- Access
- Open access
- OpenAlex
- https://openalex.org/W2521860411
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:11982147
Keywords
CTCF, Chromatin, Chromosome conformation capture, Biology, Cohesin
References
- A high-resolution map of human evolutionary constraint using 29 mammals
- CTCF Binding Polarity Determines Chromatin Looping.
- CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function
- Mitotic chromosome structure: reproducibility of folding and symmetry between sister chromatids.
- The chromatin backdrop of DNA replication: lessons from genetics and genome-scale analyses
- A three-dimensional map of the human genome at kilobase resolution reveals principles of chromatin looping
- CTCF establishes discrete functional chromatin domains at the Hox clusters during differentiation
- The long-range interaction landscape of gene promoters
- A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia.
- LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation.
- Molecular maps of the reorganization of genome – nuclear lamina interactions during differentiation
- Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture–on-chip (4C)
- Genetic and epigenetic determinants of DNA replication origins, position and activation.
- Clustering of Tissue-Specific Sub-TADs Accompanies the Regulation of HoxA Genes in Developing Limbs
- Preventing gene silencing with human replicators
- Chromosome Conformation Capture Carbon Copy (5C): a massively parallel solution for mapping interactions between genomic elements.
- Architectural protein subclasses shape 3-D organization of genomes during lineage commitment
- Chromatin loops in gene regulation
- Cohesins functionally associate with CTCF on mammalian chromosome arms.
- Chromatin Structure and Replication Origins: Determinants Of Chromosome Replication And Nuclear Organization
Cited by
- Fra-1 et Fra-2 dans les cancers du sein triple négatifs : mécanismes transcriptionnels et identification de cibles thérapeutiques potentielles
- Master-regulators driving resistance of non-small cell lung cancer cells to p53 reactivator Nutlin-3
- Identifying genomic biomarkers for cancer treatment
- Computational master-regulator search reveals mTOR and PI3K pathways responsible for low sensitivity of NCI-H292 and A427 lung cancer cell lines to cytotoxic action of p53 activator Nutlin-3
- Involvement of X-chromosome Reactivation in Augmenting Cancer Testis Antigens Expression: A Hypothesis
- Entering the Next Dimension: Plant Genomes in 3D.
- CRISPR/CAS Targeted in vivo Genome Modification for Studying the Functional Role of Genomic Regulatory Elements in Health and Carcinogenesis
- Nuclear NR4A3 Immunostaining Is a Specific and Sensitive Novel Marker for Acinic Cell Carcinoma of the Salivary Glands
- Short-range regulatory chromatin loops in plants.
- Cohesin Subunit Rad21 Binds to the Herpes Simplex Virus 1 Genome near CTCF Insulator Sites during Latency In Vivo
- Optimization of Genome Knock-In Method: Search for the Most Efficient Genome Regions for Transgene Expression in Plants
- Deletion of the CTRL2 Insulator in HSV-1 Results in the Decreased Expression of Genes Involved in Axonal Transport and Attenuates Reactivation In Vivo
- Multiple long-range cis interactions generate CTCF insulator-dependent viral chromatin domains in quiescent HSV-1 genomes
- CRISPR/CAS targeted in vivo genome modification for studying functional role of genomic regulatory elements in health and carcinogenesis
- Epigenome regulators imbue a single eukaryotic promoter with diverse gene expression dynamics
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