Collaborative overview of randomised trials of antiplatelet therapy Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients
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Summary
There was no appreciable evidence that either a higher aspirin dose or any other antiplatelet regimen was more effective than medium dose aspirin in preventing vascular events, so in each of the four main high risk categories overall mortality was significantly reduced.
- Type
- article
- Published
- 1994-01-08
- Cited by
- 3,799
- References
- 390
- OpenAlex
- https://openalex.org/W2492141817
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:78698921
Keywords
Medicine, Myocardial infarction, Stroke (engine), Randomized controlled trial, Aspirin
References
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- Randomized Clinical Trial of Daily Aspirin Therapy in Multi‐Infarct Dementia
- Effects of Suloctidil on Platelet Survival Time Following Cardiac Valve Replacement
- Administration of aspirin-dipyridamole reduces proteinuria in diabetic nephropathy.
- Publication bias: the case for an international registry of clinical trials.
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- Antiplatelet therapy for thromboprophylaxis: the need for careful consideration of the evidence from randomised trials
- Stellenwert der LDL-Apherese in der Behandlung der koronaren Herzerkrankung
- Clinical governance in Scotland: an educational model.
- Health issues in the Arab American community. The use of glucose-lowering agents and aspirin among Arab Americans with diabetes.
- Meta-analyses and overviews of randomised trials.
- Cholesterol lowering does have a role in secondary prevention.
- Children's consent to treatment
- Current Management of Peripheral Arterial Occlusive Disease
- ZD9583, an Orally Effective Thromboxane A2 Synthase Inhibitor and Receptor Antagonist with a Sustained Duration of Action in Rat and Dog
- Diabetes mellitus, hypercholesterolemia, and hypertension but not vascular disease per se are associated with persistent platelet activation in vivo. Evidence derived from the study of peripheral arterial disease.
- Clopidogrel: a new safe and effective antiplatelet agent. But unanswered questions remain
- Glucose-insulin-potassium therapy for treatment of acute myocardial infarction: an overview of randomized placebo-controlled trials.
- Screening, prevention, counseling, and treatment for the complications of type II diabetes mellitus
- Preventing stroke recurrence in patients with patent foramen ovale: antithrombotic therapy, foramen closure, or therapeutic abstention? A decision analytic perspective.
- Stroke treatment: promising but still struggling.
- Pharmacological treatment of diabetic patients with cardiovascular complications
- Current medical therapy for advanced heart failure.
- Interpretation of Thrombosis Prevention Trial.
- Effects of aspirin treatment on survival in non-insulin-dependent diabetic patients with coronary artery disease. Israeli Bezafibrate Infarction Prevention Study Group.
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