The Neuron-Specific Protein TMEM59L Mediates Oxidative Stress-Induced Cell Death
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Summary
This study indicates that TMEM59L is a pro-apoptotic neuronal protein involved in animal behaviors such as anxiety, depression, and memory, and that TM EM59L downregulation protects neurons against oxidative stress.
- Type
- article
- Published
- 2016-06-21
- Cited by
- 51
- References
- 32
- Access
- Open access
- OpenAlex
- https://openalex.org/W2472561462
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:13660679
Keywords
Downregulation and upregulation, Morris water navigation task, Programmed cell death, Cell biology, ATG5
References
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- Local Pruning of Dendrites and Spines by Caspase-3-Dependent and Proteasome-Limited Mechanisms
- The Novel Membrane Protein TMEM59 Modulates Complex Glycosylation, Cell Surface Expression, and Secretion of the Amyloid Precursor Protein*
- The Atg12-Atg5 Conjugate Has a Novel E3-like Activity for Protein Lipidation in Autophagy*
- Distinct Pathways Mediate Axon Degeneration during Apoptosis and Axon-Specific Pruning
- Diversity in the mechanisms of neuronal cell death.
- Electronic Submission to the Journal of Pharmacy and Pharmacology
- Apoptosis and liver disease.
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- Curcumin-loaded polymeric nanoparticles for neuroprotection in neonatal rats with hypoxic-ischemic encephalopathy
- Effects of High- Versus Moderate-Intensity Training on Neuroplasticity and Functional Recovery After Focal Ischemia
- Turmeric: A Review of Its Chemical Composition, Quality Control, Bioactivity, and Pharmaceutical Application
- The GluN1/GluN2B NMDA receptor and metabotropic glutamate receptor 1 negative allosteric modulator has enhanced neuroprotection in a rat subarachnoid hemorrhage model
- TMEM59 potentiates Wnt signaling by promoting signalosome formation
- Fluoxetine is Neuroprotective in Early Brain Injury via its Anti-inflammatory and Anti-apoptotic Effects in a Rat Experimental Subarachnoid Hemorrhage Model
- Chronic Metabolic Derangement-Induced Cognitive Deficits and Neurotoxicity Are Associated with REST Inactivation
- RPS23RG1 is Required for Synaptic Integrity and Rescues Alzheimer’s Associated Cognitive Deficits
- The Expression and Cellular Localisation of Neurotrophin and Neural Guidance Molecules in Peritoneal Ectopic Lesions
- Bioinspired Hydrogel Electrospun Fibers for Spinal Cord Regeneration
- Vitamin B12 Levels in Methamphetamine Addicts
- The Role of Oxidative Stress in Microvascular Disturbances after Experimental Subarachnoid Hemorrhage
- Effect of Gastrodin on Early Brain Injury and Neurological Outcome After Subarachnoid Hemorrhage in Rats
- Gene Expression Analysis of the Concomitant Existence of Lymphovascular and Perineural Invasion in Colorectal Cancer
- Metformin protects PC12 cells and hippocampal neurons from H2O 2‐induced oxidative damage through activation of AMPK pathway
- Proteomics analysis of Schwann cell-derived exosomes: a novel therapeutic strategy for central nervous system injury
- Pros and Cons: Autophagy in Acute Spinal Cord Injury
- Effects of Curcumin on Microglial Cells
- The genome of the live-bearing fish Heterandria formosa implicates a role of conserved vertebrate genes in the evolution of placental fish
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