Isolation of an HIV-1 neutralizing peptide mimicking the CXCR4 and CCR5 surface from the heavy-chain complementary determining region 3 repertoire of a viremic controller
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Summary
LRTV-1 peptide is to date the smallest human HCDR3 repertoire-derived peptide identified by phage display inhibiting HIV entry of R5 and X4 viruses, emphasizing the potential of human HC DR3 immune repertoires as sources of small biologically active peptides for HIV cure.
- Type
- article
- Published
- 2016-01-28
- Cited by
- 17
- References
- 49
- OpenAlex
- https://openalex.org/W2410343094
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:54591138
Keywords
Virology, CXCR4, Human immunodeficiency virus (HIV), Repertoire, Antibody
References
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Cited by
- Measuring Sexual Behavior Stigma to Inform Effective HIV Prevention and Treatment Programs for Key Populations
- New paradigms in chemokine receptor signal transduction: moving beyond the two-site model
- The Prevalence of Sexual Behavior Stigma Affecting Gay Men and Other Men Who Have Sex with Men Across Sub-Saharan Africa and in the United States
- Development of peptide inhibitors of HIV transmission
- Sexual stigma patterns among Nigerian men who have sex with men and their link to HIV and sexually transmitted infection prevalence
- The synergistic impact of sexual stigma and psychosocial well-being on HIV testing: A mixed-methods study among Nigerian men who have sex with men
- HIV-1 Envelope Protein gp120 Promotes Proliferation and the Activation of Glycolysis in Glioma Cell
- Stigma reduction in relation to HIV test uptake in low- and middle-income countries: a realist review
- Do combination HIV prevention programmes result in increased empowerment, inclusion and agency to demand equal rights for marginalised populations in low-income and middle-income countries? A systematic review
- High-risk behaviors and their association with awareness of HIV status among participants of a large-scale prevention intervention in Athens, Greece
- A systematic review of stigma in sexual and gender minority health interventions.
- HIV co-receptor-tropism: cellular and molecular events behind the enigmatic co-receptor switching
- Discovery of Antivirals Using Phage Display
- Downsizing antibodies: Towards complementarity-determining region (CDR)-based peptide mimetics.
- Neutralizing antibodies to block viral entry and for identification of entry inhibitors.
- Phage Display as a Medium for Target Therapy Based Drug Discovery, Review and Update
- Country meeting Prevention and control of Viral Hepatitis in Belgium and Luxembourg : lessons
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