Tissue angiotensin-converting enzyme blockade by MC-838 (altiopril calcium) infused intravenously to miniature pigs: comparison with captopril.

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Summary

Effective activities of MC-838 and captopril occurred in the lung and kidney where higher ACE activity in a variety of tissues was found, to a lesser degree in the serum and some target organs, and not at all in the brain, heart and aorta.

Type
article
Published
1988-07-01
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Keywords

Captopril, Angiotensin-converting enzyme, Bradykinin, Endocrinology, Internal medicine

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