Mesenchymal stem cells maintain their defining stem cell characteristics after treatment with cisplatin
Explore this paper's citation graph
Summary
It is demonstrated that human bone marrow-derived MSCs are relatively resistant to cisplatin treatment and show resistance levels comparable to these of differentiated fibroblasts.
- Type
- article
- Published
- 2016-01-25
- Cited by
- 36
- References
- 63
- Access
- Open access
- OpenAlex
- https://openalex.org/W2394861557
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:16845384
Keywords
Cisplatin, Mesenchymal stem cell, Stem cell, Cell biology, Cancer research
References
- Fetal kidney stem cells ameliorate cisplatin induced acute renal failure and promote renal angiogenesis.
- Mesenchymal stem cells are resistant to carbon ion radiotherapy
- Cisplatin-selected resistance is associated with increased motility and stem-like properties via activation of STAT3/Snail axis in atypical teratoid/rhabdoid tumor cells
- Intra‐Articular Injection of Mesenchymal Stem Cells for the Treatment of Osteoarthritis of the Knee: A Proof‐of‐Concept Clinical Trial
- Renal and hepatic concentrations of platinum: relationship to cisplatin time, dose, and nephrotoxicity.
- Radio-resistant mesenchymal stem cells: mechanisms of resistance and potential implications for the clinic
- Directed migration of mesenchymal cells: where signaling and the cytoskeleton meet
- Intra-renal arterial injection of autologous bone marrow mesenchymal stromal cells ameliorates cisplatin-induced acute kidney injury in a rhesus Macaque mulatta monkey model.
- Molecular basis of cellular response to cisplatin chemotherapy in non-small cell lung cancer (Review).
- Cisplatin nephrotoxicity: mechanisms and renoprotective strategies.
- Interactions of antitumor metallodrugs with serum proteins: advances in characterization using modern analytical methodology.
- Relationship between heat shock protein 60 (HSP60) mRNA expression and resistance to platinum analogues in human ovarian and bladder carcinoma cell lines.
- Cisplatin in cancer therapy: molecular mechanisms of action
- Cisplatin interaction with phosphatidylserine bilayer studied by solid-state NMR spectroscopy
- Life‐Sparing Effect of Human Cord Blood‐Mesenchymal Stem Cells in Experimental Acute Kidney Injury
- Human adipose tissue-derived mesenchymal stem cells protect kidneys from cisplatin nephrotoxicity in rats.
- Ibuprofen enhances the anticancer activity of cisplatin in lung cancer cells by inhibiting the heat shock protein 70
- Heat shock protein 90 (HSP90) is overexpressed in p16-negative oropharyngeal squamous cell carcinoma, and its inhibition in vitro potentiates the effects of chemoradiation
- Differential in vitro sensitivity of human tumor and normal cells to chemotherapeutic agents and resistance modulators
- Presence of Mesenchymal Stem Cells in Human Bone Marrow After Exposure to Chemotherapy: Evidence of Resistance to Apoptosis Induction
Cited by
- Mesenchymal stem cells exhibit resistance to topoisomerase inhibition.
- Mesenchymal stem cells are sensitive to bleomycin treatment
- Adipose mesenchymal stromal cells minimize and repair radiation-induced oral mucositis.
- Cisplatin-Impaired Adipogenic Differentiation of Adipose Mesenchymal Stem Cells 1
- Molecular markers of DNA damage and repair in cervical cancer patients treated with cisplatin neoadjuvant chemotherapy: an exploratory study
- Cisplatin radiosensitizes radioresistant human mesenchymal stem cells
- Chemotherapy-induced metastasis: Mechanisms and translational opportunities
- Human mesenchymal stem cells lose their functional properties after paclitaxel treatment
- The Radiation Resistance of Human Multipotent Mesenchymal Stromal Cells Is Independent of Their Tissue of Origin.
- MiRNA-124-3p Reduces Cell Viability in Cisplatin Resistant Neuroblastoma Cell Models.
- Application of Mesenchymal Stem Cells for Therapeutic Agent Delivery in Anti-tumor Treatment
- Mesenchymal stem cells show functional defect and decreased anti-cancer effect after exposure to chemotherapeutic drugs
- The current understanding of mesenchymal stem cells as potential attenuators of chemotherapy‐induced toxicity
- Immunomodulatory function of mesenchymal stem cells: regulation and application
- The effects of Nutlin‐3 on morphology, cellular proliferation, and apoptosis in rat primary mesenchymal stem cells
- Role of cell extrinsic and intrinsic factors in regulating mesenchymal stem cell properties
- The Therapeutic Potential of Mesenchymal Stromal Cells in the Treatment of Chemotherapy-Induced Tissue Damage
- Resistance of human primary mesenchymal stem cells to cytotoxic effects of nutlin‐3 in vitro
- Human mesenchymal stem cells are resistant to UV-B irradiation
- Multipotent mesenchymal stromal cells are sensitive to thermic stress – potential implications for therapeutic hyperthermia
Related papers
- The novel trinuclear platinum complex BBR3464 induces a cellular response different from cisplatin.
- Treatment with paclitaxel alone rather than combination with paclitaxel and cisplatin may be selective for cisplatin-resistant ovarian carcinoma.
- The Relationship between Expression of 1-Cys Peroxiredoxin and Resistance to Cisplatin in Epithelial Ovarian Cancer Cell Lines
- Modulation of cisplatin resistance by 2'-deoxy-5-azacytidine in human ovarian tumor cell lines.
- Antitumor effect of radioactive cisplatin (191Pt) on nude mice.
- Comparative antitumour activity of cisplatin and two new cisplatin-analogues JM8 and JM9 in human testicular carcinoma xenografts.
- Metoclopramide as a modulator of cisplatin: effects on pharmacokinetics and cisplatin–DNA adducts in tumor and normal tissue
- New combination chemotherapy of cisplatin with an electron-donating compound for treatment of multiple cancers
- Transarterial Chemoembolization Using Cisplatin Powder in a Rabbit Model of Liver Cancer