Pharmaceutical liposomal drug delivery: a review of new delivery systems and a look at the regulatory landscape
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Summary
The current state of the art of these new liposomal delivery systems is described and a critical overview of the current regulatory landscape surrounding commercialization efforts of higher-level complexity systems is provided, the expected requirements and the hurdles faced by companies seeking to bring novel liposome-based systems for clinical use to market are provided.
- Type
- review
- Published
- 2016-05-05
- Cited by
- 534
- References
- 91
- Access
- Open access
- OpenAlex
- https://openalex.org/W2388009875
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:27726646
Keywords
Liposome, Transdermal, Drug delivery, Commercialization, Nanotechnology
References
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- Pharmacokinetics of CPX-351; a nano-scale liposomal fixed molar ratio formulation of cytarabine:daunorubicin, in patients with advanced leukemia.
Cited by
- The Scope and Challenges of Vesicular Carrier-mediated Delivery of Docetaxel for the Management of Cancer.
- Immunomodulatory Lipocomplex Functionalized with Photosensitizer-embedded Cancer Cell Membrane Inhibits Tumor Growth and Metastasis.
- Delivering therapeutics in peripheral artery disease: challenges and future perspectives.
- Nanoyeast and Other Cell Envelope Compositions for Protein Studies and Biosensor Applications
- Effects of surface charge of low molecular weight heparin-modified cationic liposomes on drug efficacy and toxicity
- Liposomal Formulations in Clinical Use: An Updated Review
- Transdermal delivery of atorvastatin calcium from novel nanovesicular systems using polyethylene glycol fatty acid esters: Ameliorated effect without liver toxicity in poloxamer 407‐induced hyperlipidemic rats
- Improvement of skin whitening agents efficiency through encapsulation: Current state of knowledge.
- Lipid vesicles in pulsed electric fields: Fundamental principles of the membrane response and its biomedical applications.
- On-chip density-based purification of liposomes.
- Engineering liposomal nanoparticles for targeted gene therapy
- Bioengineered liposome-scaffold composites as therapeutic delivery systems.
- Sensitivity to antitubulin chemotherapeutics is potentiated by a photoactivable nanoliposome.
- Phase II study of paclitaxel associated with lipid core nanoparticles (LDE) as third-line treatment of patients with epithelial ovarian carcinoma
- Zeta potential: a case study of cationic, anionic, and neutral liposomes
- General overview of lipid–polymer hybrid nanoparticles, dendrimers, micelles, liposomes, spongosomes and cubosomes
- Application of cyclodextrins in cancer treatment
- In vitro and In vivo Studies on a Novel Bioadhesive Colloidal System: Cationic Liposomes of Ibuprofen
- Production of liposomes loaded with antioxidants using a supercritical CO2 assisted process
- In Vivo Microdialysis for Dynamic Monitoring of the Effectiveness of Nano-liposomes as Vehicles for Topical Psoralen Application.
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