Rapid analysis of diclofenac and some of its transformation products in the three-spined stickleback, Gasterosteus aculeatus, by liquid chromatography-tandem mass spectrometry
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Summary
This study deals with the analytical development of a methodology to quantify traces of diclofenac together with some of its biotic and abiotic transformation products in whole-body tissue of three-spined stickleback by QuEChERS extraction followed by LC-MS/MS.
- Type
- article
- Published
- 2016-04-16
- Cited by
- 12
- References
- 46
- OpenAlex
- https://openalex.org/W2341834780
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24564184
Keywords
Gasterosteus, Stickleback, Chromatography, Tandem mass spectrometry, Liquid chromatography–mass spectrometry
References
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- Clinical Pharmacokinetics of Diclofenac
- Occurrence of drugs in German sewage treatment plants and rivers 1 Dedicated to Professor Dr. Klaus
- Fast and easy multiresidue method employing acetonitrile extraction/partitioning and "dispersive solid-phase extraction" for the determination of pesticide residues in produce.
- Development of a method for the analysis of hormones and pharmaceuticals in earthworms by quick, easy, cheap, effective, rugged and safe (QuEChERS) extraction followed by liquid chromatography-tandem mass spectrometry (LC-MS/MS)
- Multi-residue method for the analysis of pharmaceuticals and some of their metabolites in bivalves.
- Carbamazepine and diclofenac: removal in wastewater treatment plants and occurrence in water bodies.
- Rapid analysis of pharmaceuticals and personal care products in fish plasma micro-aliquots using liquid chromatography tandem mass spectrometry.
- Diclofenac in fish: Blood plasma levels similar to human therapeutic levels affect global hepatic gene expression
- Development of an extraction and purification method for the determination of multi-class pharmaceuticals and endocrine disruptors in freshwater invertebrates.
- Ranking and prioritization of environmental risks of pharmaceuticals in surface waters.
- Solar radiation influence on the decomposition process of diclofenac in surface waters.
- Assessment of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawaters of North of Portugal: occurrence and environmental risk.
- Method for routine screening of pesticides and metabolites in meat based baby-food using extraction and gas chromatography-mass spectrometry.
- Fate of diclofenac in municipal wastewater treatment plant - a review.
- Occurrence of pharmaceutical compounds in urban wastewater: removal, mass load and environmental risk after a secondary treatment--a review.
- Analysis of multi-class pharmaceuticals in fish tissues by ultra-high-performance liquid chromatography tandem mass spectrometry.
- MicroQuEChERS-nanoliquid chromatography-nanospray-tandem mass spectrometry for the detection and quantification of trace pharmaceuticals in benthic invertebrates.
- Determination of 136 pharmaceuticals and hormones in sewage sludge using quick, easy, cheap, effective, rugged and safe extraction followed by analysis with liquid chromatography-time-of-flight-mass spectrometry.
- Pharmacological properties of five diclofenac metabolites identified in human plasma
Cited by
- Metabolic profiling identification of metabolites formed in Mediterranean mussels (Mytilus galloprovincialis) after diclofenac exposure.
- Determination of carbamazepine and 12 degradation products in various compartments of an outdoor aquatic mesocosm by reliable analytical methods based on liquid chromatography-tandem mass spectrometry
- Cytochrome P450 and Flavin-containing Monooxygenase Families: Age-Dependent Differences in Expression and Functional Activity
- A review of the pharmaceutical exposome in aquatic fauna
- Sensing of diclofenac by a porphyrin-based artificial receptor
- Occurrence, interactive effects and ecological risk of diclofenac in environmental compartments and biota - a review.
- Analysis of emerging and related pollutants in aquatic biota
- Depressed, hypertense and sore: Long-term effects of fluoxetine, propranolol and diclofenac exposure in a top predator fish.
- Effects of diclofenac on sentinel species and aquatic communities in semi-natural conditions.
- Simultaneous determination of pharmaceuticals and metabolites in fish tissue by QuEChERS extraction and UHPLC Q/Orbitrap MS analysis
- Study on the Effect of Three CYP2C9 Variants on Drug–Drug Interaction Related to Six Drugs In Vitro by LC–MS/MS Method
- Time and dose-dependent impairment of liver metabolism in Gasterosteus aculeatus following exposure to diclofenac (DCF) highlighted by LC-HRMS untargeted metabolomics.
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