Binding interaction of a prospective chemotherapeutic antibacterial drug with β-lactoglobulin: results and challenges.
Explore this paper's citation graph
Summary
A detailed characterization of the binding interaction of a potential chemotherapeutic antibacterial drug, norfloxacin (NOF), with the mammalian milk protein β-lactoglobulin (βLG) reveals the predominance of electrostatic/ionic interactions underlying the binding process.
- Type
- article
- Published
- 2014-05-15
- Cited by
- 102
- References
- 56
- OpenAlex
- https://openalex.org/W2323947683
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:43384957
Keywords
Drug, Chemistry, Pharmacology, Stereochemistry, Medicine
References
- Photophysics and photochemistry of fluoroquinolones.
- Lipid-binding proteins: a family of fatty acid and retinoid transport proteins.
- Binding Constants: The Measurement of Molecular Complex Stability
- Structure of serum albumin.
- Effect of pH on β-Lactoglobulins
- ADMET—turning chemicals into drugs
- Intrinsic Tryptophan Fluorescence of Human Serum Proteins and Related Conformational Changes
- Conformational changes of beta-lactoglobulin in sodium bis(2-ethylhexyl) sulfosuccinate reverse micelles. A fluorescence and CD study.
- Revealing two-state protein-protein interactions of calmodulin by single-molecule spectroscopy.
- Atomic structure and chemistry of human serum albumin
- BINDING MODE OF NORFLOXACIN TO CALF THYMUS DNA
- Role of the outer membrane in the accumulation of quinolones by Serratia marcescens.
- Mode of Action of Fluoroquinolones
- Reversible unfolding of a thermophilic membrane protein in phospholipid/detergent mixed micelles.
- Solute perturbation of protein fluorescence. The quenching of the tryptophyl fluorescence of model compounds and of lysozyme by iodide ion.
- One fold among many
- Unraveling the binding interaction and kinetics of a prospective anti-HIV drug with a model transport protein: results and challenges.
- Deciphering the role of pH in the binding of ciprofloxacin hydrochloride to bovine serum albumin.
- Spectroscopic Properties of Various Quinolone Antibiotics in Aqueous–organic Solvent Mixtures¶
- pH Effects on the Spectroscopic and Photochemical Behavior of Enoxacin: A Steady‐State and Time‐Resolved Study
Cited by
- Stepwise unfolding of Ribonuclease A by a biosurfactant.
- β-lactoglobulin mutation Ala86Gln improves its ligand binding and reduces its immunoreactivity.
- β-Lactoglobulin mutant Lys69Asn has attenuated IgE and increased retinol binding activity.
- Deciphering the binding patterns and conformation changes upon the bovine serum albumin-rosmarinic acid complex.
- Probing the anticancer-drug-binding-induced microenvironment alterations in subdomain IIA of human serum albumin.
- Interaction of the 5-fluorouracil analog 5-fluoro-2'-deoxyuridine with 'N' and 'B' isoforms of human serum albumin: a spectroscopic and calorimetric study.
- β-Lactoglobulin interactions with local anaesthetic drugs – Crystallographic and calorimetric studies.
- Biophysical Studies on the Interaction of Insulin with a Cationic Gemini Surfactant
- Single-Molecule Patch-Clamp FRET Microscopy Studies of NMDA Receptor Ion Channel Dynamics in Living Cells: Revealing the Multiple Conformational States Associated with a Channel at Its Electrical Off State
- The inhibitory kinetics and mechanism of dietary vitamins D3 and B2 on xanthine oxidase.
- Inverse Temperature Dependence in Static Quenching versus Calorimetric Exploration: Binding Interaction of Chloramphenicol to β-Lactoglobulin.
- Galangin competitively inhibits xanthine oxidase by a ping-pong mechanism.
- Comparative binding study of anti-tuberculosis drug pyrazinamide with serum albumins
- The interaction of beta-lactoglobulin with ciprofloxacin and kanamycin; a spectroscopic and molecular modeling approach
- Myricetin inhibits the generation of superoxide anion by reduced form of xanthine oxidase.
- Comparison of binding interaction between β-lactoglobulin and three common polyphenols using multi-spectroscopy and modeling methods.
- A Spectroscopic and Molecular Simulation Approach toward the Binding Affinity between Lysozyme and Phenazinium Dyes: An Effect on Protein Conformation.
- Probing the mechanism of interaction of metoprolol succinate with human serum albumin by spectroscopic and molecular docking analysis.
- Binding of ciprofloxacin to bovine serum albumin: Photophysical and thermodynamic aspects.
- Micro-solvation of tyrosine-kinase inhibitor AG1478 explored with fluorescence spectroscopy and computational chemistry
Related papers
- ФОРМИРОВAНИЕ ГОТОВНОСТИ БУДУЩИХ ПЕДAГОГОВ К ОРГAНИЗAЦИИ РAБОТЫ ПО РAЗВИТИЮ ВAЛЕОЛОГИЧЕСКОЙ КУЛЬТУРЫ ШКОЛЬНИКОВ
- A GEOMETRIC MEAN IN THE FURUTA INEQUALITY
- Darstellung perhalogenierter Dimethyldisulfane durch photochemische Reaktion von CSF2 und CSFCI mit Sulfenylbromiden bzw. ‐chloriden
- Chemistry of geminal diazides. Rearrangements to N-Cyano compounds
- Reaktionen mit 3-Chloro-1,2-benzisothiazolium-chloriden. Synthese von 2-substituierten 3-Amino-benzo[b]-thiophenen
- Chemistry of acetylenes