Abstract LB-84: DNA methylation centers in CpG-island promoters are context-specific

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Summary

Multiple sequences associated with very high levels of DNA methylation in normal and neoplastic tissues can be completely methylation free when inserted into a different chromatin context, and these results have important implications for the pathogenesis of aberrantmethylation in cancer.

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article
Published
2010-04-15
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Keywords

CpG site, DNA methylation, Methylation, Biology, Bisulfite sequencing

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