Zinc as an adjunct to antibiotics for the treatment of severe pneumonia in children <5 years: a meta-analysis of randomised-controlled trials
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Summary
It is suggested that adjunct treatment with Zn failed to benefit young children in the treatment of severe pneumonia.
- Type
- review
- Published
- 2016-01-26
- Cited by
- 21
- References
- 34
- Access
- Open access
- OpenAlex
- https://openalex.org/W2280593047
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:43441464
Keywords
Medicine, Adjunct, Pneumonia, Meta-analysis, Randomized controlled trial
References
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- Cochrane Handbook for Systematic Reviews of Interventions
- Zinc and immune function: the biological basis of altered resistance to infection.
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- Millennium Development Goals 4 and 5: progress and challenges
- Pneumonia research to reduce childhood mortality in the developing world.
- Short-term therapeutic role of zinc in children < 5 years of age hospitalised for severe acute lower respiratory tract infection.
- Incidence and severity of childhood pneumonia in the first year of life in a South African birth cohort: the Drakenstein Child Health Study.
- Zinc Supplementation in Severe Acute Lower Respiratory Tract Infection in Children: A Triple-Blind Randomized Placebo Controlled Trial
- Oral zinc and common childhood infections--An update.
- Zinc for severe pneumonia in very young children: double-blind placebo-controlled trial.
- Zinc and its role in immunity and inflammation.
- A Randomized Controlled Trial of Zinc as Adjuvant Therapy for Severe Pneumonia in Young Children
- Undernutrition as an underlying cause of child deaths associated with diarrhea, pneumonia, malaria, and measles.
- Synergism of nutrition, infection, and immunity: an overview.
- Role of zinc in severe pneumonia: a randomized double bind placebo controlled study
- Zinc as adjunct treatment in infants aged between 7 and 120 days with probable serious bacterial infection: a randomised, double-blind, placebo-controlled trial.
- Pulmonary defense mechanisms against pneumonia and sepsis
- Randomized, double-blind, placebo-controlled clinical trial of the efficacy of treatment with zinc or vitamin A in infants and young children with severe acute lower respiratory infection.
- Measuring inconsistency in meta-analyses
Cited by
- Role of divalent metals in infectious disease susceptibility and outcome.
- Efficacy of Oral Zinc Supplementation in Radiologically Confirmed Pneumonia: Secondary Analysis of a Randomized Controlled Trial
- Update on Prevention Efforts for Pneumonia Attributed Deaths in Children Under 5 Years of Age
- Zinc as an adjunct therapy in the management of severe pneumonia among Gambian children: randomized controlled trial
- Antimicrobial activity of ZnO nanoplates and its Ag nanocomposites: Insight into an ROS-mediated antibacterial mechanism under UV light
- Should zinc be used as an adjunct therapy in severe pneumonia in Western Europe?
- Serum vitamin and microelement nutrition of children with pneumonia and their relationship with the inflammatory state and immune response
- Therapeutic Role of Zinc Supplementation in Children Hospitalized with Pneumonia
- Zinc supplementation for pediatric pneumonia.
- Zinc Supplementation Promotes a Th1 Response and Improves Clinical Symptoms in Fewer Hours in Children With Pneumonia Younger Than 5 Years Old. A Randomized Controlled Clinical Trial
- Efficacy of Adjunctive Zinc in Improving the Treatment Outcomes in Hospitalized Children with Pneumonia: A Randomized Controlled Trial.
- A Review of Micronutrients and the Immune System–Working in Harmony to Reduce the Risk of Infection
- Efficacy of zinc as adjunctive pneumonia treatment in children aged 2 to 60 months in low-income and middle-income countries: a systematic review and meta-analysis
- Micronutrients availability, immune response, and COVID-19
- Herbal spices-based therapeutics for diabetic patients with COVID-19 infection: A review
- Zinc deficiency enhances sensitivity to influenza A associated bacterial pneumonia in mice
- A systematic review and meta‐analysis on nutritional and dietary interventions for the treatment of acute respiratory infection in pediatric patients: An EAACI taskforce
- Role of Zinc as Adjuvant Therapy in Acute Pneumonia in Clinical Recovery of Age 2 Months to 5 Years
- Effect of azithromycin combined with licorzinc therapy on inflammatory response and immune response in children with mycoplasma pneumonia
- Herbal spices-based therapeutics for diabetic patients with COVID-19 infection: A review
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