Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
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Summary
This work demonstrates the presence of exosomal and nonexosomal subpopulations within small EVs, and proposes their differential separation by immuno-isolation using either CD63, CD81, or CD9, and provides guidelines to define subtypes of EVs for future functional studies.
- Type
- article
- Published
- 2016-02-08
- Cited by
- 3,132
- References
- 57
- Access
- Open access
- OpenAlex
- https://openalex.org/W2259481044
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:38130891
Keywords
Extracellular vesicles, Extracellular vesicle, Extracellular, Biology, Computational biology
References
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Cited by
- Exosomes in Cancer Diagnostics
- Dynamics of plasma membrane surface related to the release of extracellular vesicles by mesenchymal stem cells in culture
- Exosomes from antigen-pulsed dendritic cells induce stronger antigen-specific immune responses than microvesicles in vivo
- Proteome profiling of extracellular vesicles captured with the affinity peptide Vn96: comparison of Laemmli and TRIzol© protein-extraction methods
- Cardioprotection by cardiac progenitor cell-secreted exosomes: role of pregnancy-associated plasma protein-A
- Emerging roles of extracellular vesicles in cardiac repair and rejuvenation.
- The Impact of Oncogenic EGFRvIII on the Proteome of Extracellular Vesicles Released from Glioblastoma Cells*
- Evaluation of the cardioprotective potential of extracellular vesicles – a systematic review and meta-analysis
- Liquid biopsy and NSCLC.
- Cancer Cell Signaling: Methods and Protocols
- Communication by Extracellular Vesicles: Where We Are and Where We Need to Go.
- Quantification of Exosomes
- FRMD4A–cytohesin signaling modulates the cellular release of tau
- The biology and function of exosomes in cancer.
- Phenotyping of Leukocytes and Leukocyte-Derived Extracellular Vesicles
- Extracellular Vesicles and RNA interference in tumors
- Transferring intercellular signals and traits between cancer cells: extracellular vesicles as “homing pigeons”
- Toward reliable biomarker signatures in the age of liquid biopsies - how to standardize the small RNA-Seq workflow
- Exosomes: novel implications in diagnosis and treatment of gastrointestinal cancer
- Nanoparticle analysis sheds budding insights into genetic drivers of extracellular vesicle biogenesis
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